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All Journal Indonesian Journal of Cancer Chemoprevention Pharmacon JPSCR : Journal of Pharmaceutical Science and Clinical Research Indonesian Journal of Community Services Community Empowerment Jurnal Litbang Edusaintech Jurnal Pengabdian Sumber Daya Manusia Jurnal Farmasi Sains dan Praktis Jurnal Bakti Untuk Negeri International Journal of Cell and Biomedical Science
Nur Anna Chalimah Sadyah
Universitas Islam Sultan Agung, Semarang, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Aplikasi Berbasis Mobile untuk Diabetisi dalam Menunjang Ibadah Puasa, Haji dan Umroh Kerja Sama Persadia Unit RSI Sultan Agung Sri Mulyono; Nur Anna Chalimah Sadyah; Minidian Fasitasari
Indonesian Journal of Community Services Vol 3, No 1 (2021): May 2021
Publisher : Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.3.1.73-84

Abstract

Dari data Kementerian Kesehatan dari Sampel Registration Survey 2014 menyebutkan bahwa diabetes telah menjadi penyebab kematian terbesar nomor 3 di Indonesia, dengan presentase sebesar 6,7%, setelah stroke (21,1%) dan penyakit jantung koroner (12,9%), Berdasarkan data Riskesdas 2013 (Kemenkes RI, 2013), 90% dari total kasus diabetes merupakan diabetes tipe 2, yang umumnya terjadi pada orang dewasa. Namun beberapa tahun terakhir makin banyak ditemukan pada usia dewasa muda kurang dari 30 tahun bahkan pada anak-anak dan remaja. Indonesia merupakan negara muslim terbesar di dunia. Jumlah penduduk Indonesia 258 juta 87,2% adalah warga muslim. Sebagai warga muslim disyariatkan untuk melaksanakan berbagai ibadah antara lain ibadah puasa di bulan ramadan, haji dan umroh. Pada saat puasa pasien diabetes tidak makan selama siang hari yang berpeluang menimbulkan kecenderungan makan berlebih pada malam hari. Hal ini berpotensi menyebabkan pasien 5 kali lebih berisiko mengalami hiperglikemia dan sebanyak 7 kali lebih berisiko mengalami hipoglikemia. Kegiatan edukasi program aplikasi berbasis mobile untuk diabetesi sebagai bekal dalam menjalankan ibadah puasa haji dan umroh telah dilaksanakan dengan yang diikuti oleh 348 peserta dengan berbagai unsur peserta antara lain dokter, mahasiswa kesehatan, perawat dan ibu rumah tangga. Aplikasi juga telah didistribusikan di google playstore sehingga masyarakat luas akan lebih mudah mengunduh, memasang dan memakai aplikasi tersebut dimana saja, kapan saja dengan melalui koneksi internet.Data from the Ministry of Health from the 2014 Sample Registration Survey states that diabetes has become the 3rd largest cause of death in Indonesia, with a percentage of 6.7%, after stroke (21.1%) and coronary heart disease (12.9%). Data from Riskesdas 2013 (Kemenkes RI, 2013), 90% of total diabetes cases are type 2 diabetes, which generally occurs in adults. However, in recent years, it is increasingly found in adults less than 30 years, even in children and adolescents. Indonesia is the largest Muslim country in the world. The total population of Indonesia 258 million 87.2% are Muslims. As Muslim citizens, they are obliged to carry out various acts of worship, including fasting in the month of Ramadan, Hajj and Umrah. During fasting, diabetic patients do not eat during the day which may lead to a tendency to overeat at night. This puts the patient 5 times more likely to develop hyperglycemia and 7 times more likely to develop hypoglycemia. Educational activities for mobile-based application programs for diabetes as a provision for carrying out the Hajj and Umrah fasting services have been carried out by 348 participants with various participants including doctors, health students, nurses and housewives. Applications have also been distributed on the Google Play Store so that the wider community will find it easier to download, install and use the application anywhere, anytime via an internet connection.
Kepatuhan Penggunaan Obat terhadap Profil Lipid dan Lingkar Perut pada Pasien Sindrom Metabolik di Rumah Sakit di Semarang Farroh Bintang Sabiti; Nur Anna Chalimah Sa’dyah; Ayu Pambajeng Puspitaningrum
Pharmacon: Jurnal Farmasi Indonesia Vol 18, No 2 (2021)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v18i2.16299

Abstract

Metabolic syndrome is a metabolic disorder caused by a complex increase in obesity. Metabolic syndrome can be controlled by adhering to medication and a healthy lifestyle. Patient's behavior towards adherence to medication is carried out in order to achieve the goal of treatment itself. The research objective was to determine the effect of medication adherence on lipid profiles and abdominal circumference in metabolic syndrome (SM) patients at Hospital in Semarang. This research is an observational research. Data were collected using a cross sectional design. Data collection in this study was conducted in August - December 2020. This study used the chi-square test, the chi-square test for abdominal circumference obtained results of 0.254 which said there was no effect of drug adherence with the abdominal circumference value and the chi-square test. for LDL, the results were 0.046 and the results were 0.001 for triglycerides, which is said to have an effect on drug adherence to LDL levels and trglyceride levels. The conclusion in this study is that there is an effect of patient drug use adherence to LDL (Low Density Lipoprotein) and triglyceride levels, while there is no effect of patient drug use adherence to abdominal circumference values.
The Role of Hypoxic Mesenchymal Stem Cells Conditioned Medium in Increasing Vascular Endothelial Growth Factors (VEGF) Levels and Collagen Synthesis to Accelerate Wound Healing Hadi Sunarto; Setyo Trisnadi; Agung Putra; Nur Anna Chalimah Sa'dyah; Arya Tjipta; Chodidjah Chodidjah
Indonesian Journal of Cancer Chemoprevention Vol 11, No 3 (2020)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev11iss3pp134-143

Abstract

Full-thickness wound are areas damage of skin associated with loss of epidermis and dermis. The wound healing mechanism consists proliferation, migration and remodeling. Hypoxic conditional medium of mesenchymal stem cells (HMSCs-CM) contains lots of soluble molecules, such as protein growth factor and cytokine anti-inflammation. The soluble molecule of HMSCs-CM plays a critical role in wound healing by upregulation of VEGF and collagen synthesis. The objective of this study was to evaluate the effect of HMSCs-CM on VEGF and collagen concentrations in rats with incised wounds. The methods of this study were an experimental animal study with post-test only control group design was performed involving 24 Wistar rats. The rats were randomized into four groups consisting of sham, control and two treatment groups (gel of HMSCs-CM at doses of 200 μL and 400 μL). The VEGF levels and collagen density were analyses using ELISA assay and Masson-trichome specific staining, respectively. One-way ANOVA and Post Hoc LSD were used to analyses the data. The results of this study showed that a VEGF levels was significant increased on day 6 with doses-dependent manner. Interestingly, the VEGF levels gradual decrease on day 9. In addition, the decreased of VEGF levels on day 9 in this study in line with our findings in which we found there was a trend in the decreased of collagen density, it indicated the completion of remodeling phase and there has been an acceleration in wound healing. This study demonstrated that HMSCs-CM were able to regulate VEGF levels and collagen synthesis in accelerate wound healing. The role of HMSCs-CM stimulate cutaneous wound healing should be clarified further.Keywords: hypoxic conditional medium of mesenchymal stem cells (HMSCs-CM), vascular endothelial growth factor, collagen synthesis, paracrine factors
A EFFECT OF STRENUOUS PHYSICAL ACTIVITY ON THE SUM OF LEUKOCYTES IN WISTAR STRAIN MALE MICE : A EFFECT OF STRENUOUS PHYSICAL ACTIVITY ON THE SUM OF LEUKOCYTES IN WISTAR STRAIN MALE MICE Annisa Nurul Hikmah; Chodidjah Chodidjah; Nur Anna Chalimah Sadyah
Jurnal Litbang Edusaintech Vol. 1 No. 1 (2020): Volume 1 No 1 2020
Publisher : Litbang PWM Jawa Tengah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51402/jle.v1i1.1

Abstract

This research aims to determine the effect of strenuous physical activity on the sum of leukocytes. The study used experimentally with the posttest only control group design approach. The study subjects of 10 male mice were randomly divided into two groups. The control group was not given heavy physical activity and the treatment group was given heavy physical activity. On the 27th day of blood retrieval for an examination of the sum of leukocytes in the Integrated Biomedical Laboratory, in July-August 2020. The mean on the sum of leukocytes increased in the treatment group compared to the control group. The Mann Whitney test showed that the sum of leukocytes in the control group was significantly different from the treatment group with a value of p = 0.009 (p <0.05). More research is needed on strenuous physical activity in IL-6 levels and calculates leukocytes as one of the study boosters. This research can be used as a reference in the control of the immune system of the body.
Kepatuhan Pengobatan Terhadap Indeks Glikemik Kontrol Pada Pasien Diabetes Melitus Tipe II di Rumah Sakit Islam Sultan Agung Semarang Nur Anna Chalimah Sa’dyah; Farroh Bintang Sabiti; Sandra Thertianing Susilo
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 6, No 3 (2021)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v6i3.51930

Abstract

Diabetes Melitus ialah penyakit yang ditandai dengan nilai kadar HbA1c >7%. Hampir 80% pasien Diabetes Mellitus Tipe II mengalami kematian. Kepatuhan dalam meminum obat merupakan peran penting bagi penderita penyakit Diabetes Melitus tipe II. Perlu adanya peningkatan kepatuhan dalam penggunaan obat sehingga keberhasilan dalam pengobatan tercapai serta nilai kadar indeks glikemik yang terkontrol. Tujuan penelitian ini adalah untuk mengetahui hubungan kepatuhan penggunaan obat dengan indeks glikemik kontrol pada pasien Diabetes Melitus di Rumah Sakit Islam Sultan Agung Semarang. Penelitian ini merupakan penelitian pra-eksperimental dengan rancangan The one Group Pretest-Posttes dilakukan secara cross sectional. Sampel sebanyak 96 pasien yang diberikan kuisioner kepatuhan ARMS diambil di Rumah Sakit Islam Sultan Agung Semarang Pengambilan data dilakukan pada periode Agustus-Oktober 2020 di Rumah Sakit Islam Sultan Agung Semarang. Penelitian ini didapatkan hasil 0,000 yang dikatakan terdapat indeks glikemik kontrol HbA1c pada pasien Diabetes Melitus type II di Rumah Sakit Islam Sultan Agung Semarang menunjukan nilai p 0,000 (p < 0,05) bahwa terdapat hubungan kepatuhan penggunaan obat dengan Indeks glikemik kontrol kadar HbA1c.
EDUKASI PENCEGAHAN KOMPLIKASI DIABETES MELLITUS PADA MATA Harka Prasetya; Nur Anna Chalimah Sa'dyah; Minidian Fasitasari; Suparmi
Jurnal Pengabdian Sumber Daya Manusia Vol. 1 No. 2 (2021): EDISI OKTOBER 2021
Publisher : Scholar Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (550.626 KB)

Abstract

Diabetes mellitus (DM) merupakan salah faktor risiko dari komplikasi pada mata terutama retinopati diabetika, Oleh karena itu skrining DM secara teratur pada semua pasien DM (diabetisi) dapat membantu dalam deteksi dini dan pengelolaan komplikasi pada mata. Edukasi dilaksanakan secara daring menggunakan fitur online meeting dari Zoom. Pemaparan materi melalui metode ceramah terdir dari 3 sesi : (1) pencegahan komplikasi mata dengan pengendalian DM, (2) komplikasi DM pada mata, (3) pengaturan diabetisi. Keberhasilan pelaksanaan edukasi dilihat berdasarkan peningkatan tingkat pemahaman peserta berdasarkan nilai pre-test da post-test. Data dianalisa menggunakan analisis T-test (paired two samples for means) pada Prism 9 for macOS. Hasil penilaian kuesioner yang diisikan oleh peserta menunjukkan bahwa sebanyak 46.7% dari 60 peserta mengalami kenaikan nilai setelah edukasi (post-test) dibandingkan dengan nilai sebelum paparan materi disampaikan (pre-test), meskipun tidak berbeda secara signifikan (p>0,05). Sebanyak 18.3% peserta mengalami penurunan tingkat pemahaman tentang materi yang disampaikan. Edukasi online tentang pencegahan komplikasi DM pada mata bermanfaat sebagai upaya meningkatkan best practice pemahaman peserta mengenai langkah-langkah dalam menangani komplikasi mata akibat DM. Kata kunci: diabetes mellitus (DM), diabetisi, edukasi, komplikasi mata, nutrisi
Training on monitoring side effects of diabetes mellitus drugs for Persadia members Farroh Bintang Sabiti; Nur Anna Chalimah Sa’dyah
Community Empowerment Vol 7 No 5 (2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.774 KB) | DOI: 10.31603/ce.6320

Abstract

People with diabetes are often unaware of the side effects of the medications they take, including both oral diabetic medications and insulin. This program is provided in an effort to empower the Indonesian Diabetes Association (Persadia) Semarang City Branch's training on monitoring pharmacological side effects in diabetes mellitus patients who are self-isolating. It is hoped that by participating in this activity, drug compliance would improve, the death rate from diabetes will reduce, and the complexity of comorbidities will be avoided. The results of implementing this program, namely monitoring the side effects of taking diabetic mellitus drugs in Persadia members, can raise understanding of side effect symptoms, resulting in increased adherence to diabetes drug use and better blood sugar control.
PEMANTAUAN GULA DARAH MANDIRI DIMASA PANDEMIC COVID 19 PADA PASIEN DIABETES MILITUS ANGGOTA PERSADIA KOTA SEMARANG Nur Anna Chalimah Sa'dyah; Farroh Bintang Sabiti
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.802 KB)

Abstract

People with diabetes who join the Indonesian Diabetes Association (PERSADIA) Semarang have around 150 members and many activities are carried out with the aim of controlling the condition of disease disorders due to Diabetes Mellitus (DM), activities in the form of joint gymnastics and training activities. Since the COVID19 pandemic occurred, all activities havebeen stopped because people with DM are a vulnerable population to be affected by COVID. Many DM sufferers even contracted COVID and had to do ISOMAN so they were constrained not being able to do a blood glucose examination. Purpose: to provide knowledge and monitoring blood glucose levels using a glucometer so can increase knowledge by practicing at home. Implementation are data collection of PERSADIA members, preparation of materials, implementation and documentation of activities and reports. The material presented is monitoring blood glucose levels independently with a glucometer. Documentation of activities is carried out in the form of photos of activities and reports which are one of the evidence of the implementation that has been carried out The conclusion that the service activities providing training on monitoring blood glucose levels in DM patients with a glucometer device who are self-isolating members of Persadia Semarang an increase knowledge so that patients practice at home.Keywords: checks blood glucose, PERSADIA, training
THE RELATIONSHIP BETWEEN SIDE EFFECTS OF TUBERCULOSIS DRUG USE AND SGOT/SGPT VALUE OF INTENSIVE PHASE PATIENTS Farroh Bintang Sabiti; Nur Anna Chalimah Sa’dyah
Jurnal Farmasi Sains dan Praktis Vol 8 No 3 (September-December 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i3.4721

Abstract

Tuberculosis is an infectious disease caused by the bacteria Mycobacterium Tuberculosis which has a rod shape and is acid-resistant. The prolonged consumption of anti-tuberculosis drugs can cause serious side effects. Side effects from the consumption of anti-tuberculosis drugs, namely the risk of hepatotoxicity, which is marked by an increase in the SGOT / SGPT value. This study aimed to determine the relationship between the duration of use, dosage and side effects of anti-tuberculosis drugs in tuberculosis patients, which had an effect on the SGOT / SGPT value at RSI Sultan Agung Semarang. This research is an analytical observational study with a cross-sectional design. The sample was 96 patients, and data collection was carried out in January-November 2020 at RSI Semarang. The instrument used in this study was patient medic record data. This study uses the Chi-Square test. The Chi-Square test results in 0.000 (p <0.05) so that it could be stated that there was a relationship between the use and side effects on the SGOT / SGPT value.
PEMANTAUAN GULA DARAH MANDIRI DIMASA PANDEMIC COVID 19 PADA PASIEN DIABETES MILITUS ANGGOTA PERSADIA KOTA SEMARANG Nur Anna Chalimah Sa'dyah; Farroh Bintang Sabiti
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jbn.v2i2.1088

Abstract

People with diabetes who join the Indonesian Diabetes Association (PERSADIA) Semarang have around 150 members and many activities are carried out with the aim of controlling the condition of disease disorders due to Diabetes Mellitus (DM), activities in the form of joint gymnastics and training activities. Since the COVID19 pandemic occurred, all activities havebeen stopped because people with DM are a vulnerable population to be affected by COVID. Many DM sufferers even contracted COVID and had to do ISOMAN so they were constrained not being able to do a blood glucose examination. Purpose: to provide knowledge and monitoring blood glucose levels using a glucometer so can increase knowledge by practicing at home. Implementation are data collection of PERSADIA members, preparation of materials, implementation and documentation of activities and reports. The material presented is monitoring blood glucose levels independently with a glucometer. Documentation of activities is carried out in the form of photos of activities and reports which are one of the evidence of the implementation that has been carried out The conclusion that the service activities providing training on monitoring blood glucose levels in DM patients with a glucometer device who are self-isolating members of Persadia Semarang an increase knowledge so that patients practice at home.Keywords: checks blood glucose, PERSADIA, training
Co-Authors Agung Putra Annisa Nurul Hikmah Ayu Pambajeng Puspitaningrum Azizah Retno Kustyah Chodidjah Chodidjah Chodidjah Chodidjah Hadi Sunarto Harka Prasetya Hudan Taufiq Minidian Fasitasari Minidian Fasitasari Rizqi Windhu Sri Istania Sabiti, Farroh Bintang Sandra Thertianing Susilo Setyo Trisnadi Sri Mulyono Suparmi Tjipta, Arya