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All Journal Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kesehatan
Bela Novita Amaris Susanto
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Ilmiah Biosaintropis (Bioscience-Tropic)

 1 
Pengaruh Ekstrak Batang Bajakah Tampala (Spatholobus littoralis Hassk) Terhadap Perilaku Mencit Jantan (Mus musculus) yang Terinfeksi Bakteri Salmonella typhimurium Bela Novita Amaris Susanto; Nofri Zayani; Nindita Clourisa Amaris Susanto
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 7 No 2 (2022): Januari 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (562.231 KB) | DOI: 10.33474/e-jbst.v7i2.479

Abstract

Bajakah tampala stem (Spatholobus Littoralis Hassk) has the potential to be used for health, especially to increase immunity. The results of the phytochemical screening test showed that the main ingredients of bajakah were saponins, flavonoids, and tannins. The study used an experimental design with a completely randomized design (CRD), which consisted of 5 treatments (dose) and 6 replications. The dose is aquadest (K1/control); 25 mg/kg (K2); 50 mg/kg (K3); 100 mg/kg bw (K4) and 30 mg/kg of brand X immunomodulatory drug (K2). Mice were injected orally with the treatment according to the prescribed dose for 30 days. On the 31st day, the mice were infected with Salmonella typhimurium bacteria. On the 32nd-34th day, physical condition and activity were observed. data on changes in physical condition and activity were processed by descriptive statistics. Batang bajakah tampala extract (Spatholobus littoralis Hask) can improve the immune system as seen from the behavior and external morphology of mice (Mus Musculus) exposed to salmonella typhimurium, especially at a dose of K4 (100 mg/kg bw). Keywords: Bajakah tampala, behavior, mice, salmonella typhimurium
Efek Antiinflamasi dan Antipiretik Ekstrak Batang Bajakah Tampala (Spatholobus littoralis Hassk) pada Mencit (Mus musculus L.) nofri - zayani; Bela Novita Amaris Susanto; Eva Marsepa
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 8 No 1 (2022): Agustus 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (557.813 KB) | DOI: 10.33474/e-jbst.v8i1.491

Abstract

Exploration of the plants used to treat inflammation and fever continues to grow. One of the plants with great potential is Bajakah tampala (Spatholobus littoralis Hassk). Phytochemical test results showed bajakah contains flavonoids, tannins, saponins, phenolics, and terpenoids that function as anti-inflammatory and antipyretic so as to reduce inflammation and fever. The purpose of this study was to examine the anti-inflammatory effect of Bajakah stem extract (EBB) on the edema area and leukocyte numbers, as well as its antipyretic effect on the rectal temperature of mices. Total experimental study design with a completely randomized factorial design consisted of 5 treatments (EBB doses 0, 25, 50, 100 and aspirin 80 mg/kg) and 4 replications. EBB was extracted by maceration with 70% ethanol. Mices used were 20 healthy males, aged 13-14 weeks, and weighed 30-35 grams. 1% carrageenan was used to induce inflammation and baker's yeast was used to induce fever. EBB is given orally after 30 minutes of inflammation and an increase in rectal temperature. Data were analyzed by variance analysis (ANOVA) and continued with Duncan Multiple Range Test (DMRT) at 1% level. The results showed that EBB administration had an effect on reducing edema area and leukocyte numbers after 1% carrageenan induced, and the rectal temperature of mices after baker's yeast induced. In conclusion, EBB has good anti-inflammatory and antipyretic effects with the most effective dose of 25 mg/kg. Keywords: Bajakah tampala, Edema, Leukocytes, Rectal temperature
Efek Pemberian Suspensi Buah Zuriat (Hyphaene thebaica) terhadap Morfometri Ovarium Mencit (Mus musculus L.) yang Terpapar Asap Rokok Nofri Zayani; Bela Novita Amaris Susanto; Solihati Solihati
Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Vol 8 No 2 (2023): Januari 2023
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/e-jbst.v8i2.514

Abstract

Co-Authors Annisa Diyan Meitasari Eva Marsepa Luthfia Mar’atushsholihah Nadya Karlina Megananda Nindita Clourisa Amaris Susanto nofri - zayani Nofri Zayani Nofri Zayani Ratna Setiyaningsih Sholichah Rohmani Solihati Solihati Ulfa Afrinurfadhillah Darojati