Regina Regina
Department of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

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The correlation between skin type and acne scar severity in young adults Yessica Mishellin Awaloei; Nawanto Agung Prastowo; Regina Regina
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 1, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss1.art9

Abstract

Background: Acne is the most common skin disorder, especially in adolescents and youths. Inflammation due to acne may leave scar tissue. The scar severity may correlate with gender and skin type. Objective: This study aims to investigate the correlation between gender, skin type, and acne scar severity in youth. Methods: This is a cross-sectional study with 132 (81 female) medical college students aged from 18 to 23 participated in the study. Skin type was assessed using a Baumann Skin Type questionnaire. Acne scar severity was evaluated using the Qualitative Global Scarring Grading. Skin examination was conducted through the image from the face photograph. Lambda test was used to confirm the correlation between gender, skin type, and acne scar severity. Multiple logistic regression was applied to determine the odd risk of gender and skin type to moderate-severe acne scar. Significance was set at p<0.05.Results: Most of the participants (80.3%) had oily skin, and 22 participants (16.7%) had moderate-severe acne scar. A weak positive correlation was confirmed between skin type and acne scar severity (p<0.01, r=0.3). Oily skin type has 4.3 times greater risk of developing more severe acne scar (p<0.01, 95%CI = 1.90-9.90).Conclusion: Skin type is correlated with acne scar severity. Oily skin type is at greater risk of developing severe acne scar.
Association between melanin and vitamin D: A systematic review Andre Colin Hartono; Veronika Maria Sidharta; Yunisa Astiarani; Regina Regina
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 14, No 1, (2023)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol14.Iss1.art13

Abstract

Globally, there is an increasing prevalence of vitamin D deficiency, including in Southeast Asia, which ranges from 6% to 70%. Vitamin D plays an important role in calcium metabolism and bone health. Melanin is one factor that contributes to vitamin D deficiency. It has photoprotective properties that inhibit vitamin D synthesis, but the mechanism has not been fully understood. To determine the mechanism of the association between melanin and vitamin D, this systematic review was conducted on 11 articles, including cross-sectional studies, cohort studies, and randomised controlled trials published from 2010 to 2020. The search included Pubmed, EBSCO, and Proquest databases, and data were synthesised from 11 studies. This critical review found nine of the 11 studies reported a significant association between melanin and vitamin D, while two reported non-significant results. Of the nine significant studies, eight reported that people with higher melanin have lower vitamin D levels, while one study suggested that melanin levels do not necessarily associate with lower vitamin D levels. In conclusion, the review establishes a significant association between melanin and vitamin D.