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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science)
Hendra Perkasa
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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Efektivitas HE4 sebagai Metode Skrining Terbaru untuk Diagnosis Dini Kanker Ovarium Amru Sofian; Hendra Perkasa; Ega Rahman Evsya; Riyan M Darundryo
Jurnal Ilmu Kedokteran Vol 5, No 2 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.844 KB) | DOI: 10.26891/JIK.v5i2.2011.88-93

Abstract

The tumor marker CA125 is one of the currently used biomarkers to detect ovarian cancer. The tumormarker CA125 also elevated in other diseases. Human epididymis protein 4 is used as a new biomarker forearly detection of ovarian cancer. Human epididymis protein 4 is increased in almost all patients withovarian cancer and increased only slightly at a fraction of other diseases. Human epididymis protein 4 hasa better effectiveness in detecting ovarian cancer when combined with CA125. From the study of literaturefound that the combination of HE4 and CA125 had a specificity of 96.3% and 92.9% sensitivity.
Co-Authors Amru Sofian Ega Rahman Evsya Riyan M Darundryo