This research is aimed to analyze the efficiency of NPK fertilization by application of Arbuscular Mycorrhiza Fungi (AMF) to p-available, uptake p and growth of local pepper seeds in Aceh on soil media inceptisols. The research was conducted Agriculture Experimental Garden, Malikussaleh University. Implementation of the research was also conducted at Agroecotechnology Laboratory, Faculty of Agriculture, Malikussaleh University and Laboratory Center for Assessment Agricultural Technology (BPTP) Aceh. The study was conducted from January to December 2017. The study design was arranged in a Randomized Block Design with three replications. The first factor is dose of FMA with dose levels 0, 12,5; 25; and 37.5 g / plant. The second factor is NPK fertilizer with dose levels 0, 10, 20, and 30 g / plant. The observed variables included AMF infections in plant roots, analysis of soil chemical properties (pH H2O, and P-available); P-uptake, and plant growth (dry weight of the roots and dry weight of the canopy). The observed data were analyzed by using F test. The average comparison of treatments were analyzed by BNT test at 0.05 level. The results showed that the dose of AMF had no effect on soil pH value, P uptake and dry weight of canopy. The research revealed that the best NPK fertilizer dose was 10 g polybag-1 which increases the nutrient uptake of P and the dry weight of the canopy. The higher the doses of NPK fertilizer we used, it lowered the growth of the plant. We found that the best interaction happened in combination between the dose FMA 37.5 g polybag-1 with the dose of NPK 10 g polybag-1 The combination can increase the AMF infection, P-available and dry weight of roots. The higher the dose of AMF, the lower the need for NPK fertilizer. The use of AMF was efficient in the use of NPK fertilizer on local pepper cuttings in Aceh in soil media inceptisols in Reuleut.