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Nabilah S. A. Tamrin
Department of Defence Science, National Defence University of Malaysia
Engineering Other

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Simulated data of urea of haemodialysis patient using one-compartment model Nabilah S. A. Tamrin; Noorddin Ibrahim
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 3, No 1 (2013): Life Sciences
Publisher : Syiah Kuala University

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Abstract

End stage kidney disease (ESKD) is a disease where both kidneys are no longer functioning properly and patients require renal replacement therapy (RRT) such as haemodialysis to prolong their life. The numbers of modality for haemodialysis had increased, as the numbers of new patient of ESKD increased. In Malaysia, the numbers of new patient had increased three-fold for the past 10 years, from year 2002 to year 2012. In this paper, demographic data, clinical data and input and output of dialysis for the selected patients are presented. The post-dialysis urea concentrations for each patient with different weightfor one compartment model were simulated using MATLAB software. The simulated values of post-dialysis urea concentration were then compared with the clinical values of post-dialysis urea concentration for different weight. The simulated values of post-dialysis urea concentration underestimated the clinical value of post-dialysis urea concentration for patient with weight less than 70kg but overestimated to patient with weight greater than 70kg. The ratio of simulated values and clinical values of post-dialysis urea concentration were found to increase with the weight of patient
Co-Authors Noorddin Ibrahim