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All Journal Jurnal Natur Indonesia SAINSMAT Jurnal Online Mahasiswa (JOM) Bidang Pertanian Indonesia Chimica Acta INSIST (International Series on Interdisciplinary Research) Inovasi Pendidikan: Jurnal Pendidikan
Netti Herawati
Universitas Negeri Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Languange, Linguistic, Communication & Media Mathematics Other

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Journal : Jurnal Natur Indonesia

 1 
3,3’-di-O-methylellagic acid, an Antioxidant Phenolics Compound from Sonneratia alba Bark Herawati, Netti; Firdaus, Firdaus
Jurnal Natur Indonesia Vol 15, No 1 (2013)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.904 KB) | DOI: 10.31258/jnat.15.1.63-67

Abstract

Free radicals play an important role in some pathogenesis of serious diseases, such as neurodegenerative disorders, cancer,liver cirrhosis, cardiovascular diseases, atherosclerosis, cataracts, diabetes and inflammation. Compounds that can scavengefree radicals have great potential in ameliorating these diseases. It is reported that phenolic compounds in plants possessstrong antioxidant activity and may help to protect cells against the oxidative damage caused by free radicals. Previousstudy revealed that mangrove trees, Sonneratia alba Bark showed strong antioxidant activity. Ethyl acetate fractionexhibited the best antioxidant performance. The antioxidant activity of this fraction was attributed to the presence ofcompounds of different polarities such as phenolics. Furthermore, the phenolic antioxidant of ethyl acetate fraction werepurified and identified with UV, IR, MS, and 2D NMR spectrometry. 3,3’-di-O-methylellagic acid was found in brownamourphous powder. Antioxidant activity was evaluated and compared with L-(+)-ascorbic acid as standard by usingDPPH assay. The compound has strong antioxidant activity than ascorbic acid standar with the value of IC 50 11.35 and17.64 μg/mL, respectively. The high value of antioxidant activity of compound indicate that S. alba is a potential source ofnatural antioxidant agent.
Co-Authors ', Rahmayuni ', Syahrial . Alimin, . A. Zulfikar Effendi, A. Zulfikar Andriyani Fadmi Army Auliah Astriani, Sulis Chandra, Rani Dewi Fortuna Ayu Edi Setiawan Eri Setiawan Ervissa N Sipayung Faizah Hamzah Fajar Restuhadi Fajri, Annur Firdaus Zenta Gultom, Adi Hizkia GUSTIAWAN, SANDY Hamzah, Farida Hanum Hasan, Sri Wahyuni Ilmiah, Ide Khoirin Nisa LA DAHA Mohammad WIJAYA Muhaedah Rasyid Muhammad Anwar Muhammad Danial Muhammad Rakib Muhammad Rivai Noor Jalaluddin Prastika, Ike Priyatmo, Yudhi Putri, Kurnia Rano, Felisitas Yanti Raswen Efendi Risdawati, Risdawati Rossi, Evy SARI, SELVI MUSTIKA Selvianti H, Fifi Silaban, Mastrina Sonyinga, Desma Sonyinga, Desma Sugiarti Sugiarti sulistianingsih, Yuni Syarifuddin, Ulben Taty Sulastry Vonny Setiaries Johan Wulandari, Ayu Sri Yelmira Zalfiatri Yusmarini Yusmarini