Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Research Journal of Life Science

Application of Optimal Control Strategies for the Spread of HIV in a Population Marsudi Marsudi; Noor Hidayat; Ratno Bagus Edy Wibowo
Research Journal of Life Science Vol 4, No 1 (2017)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.253 KB) | DOI: 10.21776/ub.rjls.2017.004.01.1

Abstract

This paper presents an application of optimal control theory to assess the effectiveness of control measures on the spread of HIV in a population.  This paper formulates and analyzes a deterministic mathematical model with use of condom, screening and therapy as control variables using optimal control theory and Pontryagin’s Maximum Principle. It formulates the appropriate optimal control problem and investigate the necessary conditions for the disease control in order to determine the role of unaware infectives in the spread of HIV using of condom, screening of unaware infective and antiretroviral therapy are used as the control items. The optimality system is derived and solved numerically.