The chemical ladder snake game is one of the variations in learning media in doing practice questions. This type of research is Research and Development (R and D) using the 4-D model which includes the stages of define, design, develop, and disseminate. The research is limited to the develop part of the validity test. The instrument used was a validity questionnaire given to two UNP chemistry lecturers and two chemistry teachers at SMA N 3 Padang. Data collection techniques were analysed using Aiken V formula. Data analysis showed that the level validity of the chemical ladder snake was 0,75, so it can be concluded that the chemical ladder snake developed was valid as a learning media for the acid-base material of class XI SMA or MA.