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Metabolite Variation of Peanut Hulls (Arachis hypogaea L.) from Three Locations of Lombok Island on the Basis of GC-MS Analysis Surya Hadi; Dina Asnawati; Baiq Mariana; Hijriati Sholehah; Andhina Rizkya Satriani; Seto Priyambodo
The Journal of Pure and Applied Chemistry Research Vol 6, No 3 (2017): Edition of September - December 2017
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1025.206 KB) | DOI: 10.21776/ub.jpacr.2017.006.03.328

Abstract

This article is a part of studies to investigate the potential of natural products from Lombok Island for antidiabetic agents. This study was directed to learn the metabolite variations of peanut hulls collected from three different locations in Lombok Island. The hull samples were extracted in methanol, followed by partition process into three fractions using three solvents with varied polarities (dichloromethane, hexane and acetone). The fractions were then separated and identified for their chemical composition by using GC-MS instrument. Metabolite variations of three extracts showed that the antidiabetic compounds stigmast-5-en-3-ol and oleic acid were found in all three locations with different percentages of abundance. Another antidiabetic compound, linoleic acid, was only identified in peanut hulls from the village of Pringga Jurang (PJ). Besides the antidiabetic compounds, there were other major compounds with known biological activities discussed to find other uses of the hulls.
Differences In Lipid Profiles Based on Physical Activity Levels Among First-Year Students In a Medical Education Research Program Ida Ayu Eka Widiastuti; Seto Priyambodo; Rifana Cholidah
Jurnal Penelitian Pendidikan IPA Vol 9 No 2 (2023): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i2.3627

Abstract

Regular physical activity with adequate intensity, according to WHO recommendations, can prevent various chronic diseases, such as heart disease, diabetes mellitus, cancer, and bone disease. Physical activity can improve lipid profil: triglycerides, total cholesterol, HDL cholesterol (HDL-C), and LDL cholesterol (LDL-C). The aim of this study was to compare lipid profiles, which include levels of triglycerides, total cholesterol, HDL cholesterol (HDL-C), and LDL cholesterol (LDL-C) at different levels of physical activity: low, medium, and high levels of physical activity. This study was an observational analytic study using a cross-sectional study. The subjects of this study were 93 first year students of the Medical Study Program, Faculty of Medicine, University of Mataram. The level of physical activity was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) questionnaire and the lipid profile levels were measured using the enzymatic calorimetric method. The Kruskal-Wallis test was performed to assess the comparison of triglyceride levels between groups with low, medium and high activity levels, One-way ANOVA test for total cholesterol, LDL-C and HDL-C levels, and Post Hoc LSD for HDL-C. Of the 93 subjects, 36 (38.71%) had low levels of physical activity, 49 (52.69%) moderate physical activity, and only 8 (8.6%) had high levels of physical activity. There was a significant difference in HDL-C in the high-moderate physical activity level (p=0.006), high-low physical activity level (p=0.006), and medium-low physical activity level (p=0.022). Based on the results of this study, it can be concluded that there are significant differences in HDL-C at all levels of physical activity. Regular, measured physical activity of moderate to high intensity can increase HDL-C