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Pengaruh Kadar Gula Darah terhadap Kejadian Reinfark dan Kematian pada Penderita Sindroma Koroner Akut Jamaludin Jamaludin; Zaenab Djafar
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 1 (2015)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.397 KB) | DOI: 10.46496/medula.v3i1.2540

Abstract

Recent decades data relates between admission hyperglycemia and mortality that increase among acute coronary syndrome(ACS) patients. Aim  of study is to assess relationship between hyperglycemia and Cardiac Event, i.e. death, reinfarction among ACS patients. This is a prospective cohort study, which was held on March to April 2014 among 83 ACS patients in CVCU Wahodin Sudorohusodo Hospital. Patients was grouped into two groups, hyperglycemic ACS group and normoglycemic one. Reinfarction and death events at each group was observed within first 30 days after infarction. In this study, it found death and reinfarction events were higher in hyperglycemic group than in normoglycemic group (22 vs 4, RR = 3.7, p=0.026 for death event, and 14 vs 1, RR =8.7, p=0.03 for reinfarction). Conclusion of this study was hyperglycemia is related to reinfartion and death events among ACS patients.Keywords: Acute Coronary Syndrome, Hyperglycemia, Reinfarction, Death
Nilai Prognostik Hiperglikemia terhadap Kejadian Gagal Jantung pada Penderita Sindroma Koroner Akut Jamaluddin Jamaluddin; Zaenab Djafar
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 5, No 2 (2018)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.707 KB) | DOI: 10.46496/medula.v5i2.4374

Abstract

Hyperglycemia is a important prognostic factor in acute coronary syndrome patients. Recent decades data shows significant relationship between  admission hyperglycemia and heart failure that increase among acute coronary syndrome(ACS) patients.  Aim  of study is to assess relationship between hyperglycemia and heart failure among ACS patients. This is a prospective cohort study, which was held on March to April 2014 among 83 ACS patients in CVCU Wahodin Sudorohusodo Hospital. Patients was grouped into two groups, hyperglycemic ACS group and normoglycemic one. Heart failure events at each group was observed within first 30 days after infarction. In this study, it found heart failure event were higher in hyperglycemic group than in normoglycemic group (30 vs 8, RR 2.7, p = 0.04). Conclusion of this study was hyperglycemia is related to heart failure event among ACS patients.Keyword: acute coronary syndrome, hyperglycemia, heart falure
POTASSIUM MONITORING IN HEART FAILURE PATIENTS RECEIVING COMBINED THERAPY OF CAPTOPRIL AND FUROSEMIDE Hubby Hubby; Suharjono Suharjono; Zaenab Djafar
Folia Medica Indonesiana Vol. 52 No. 4 (2016): OCTOBER - DECEMBER 2016
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.045 KB) | DOI: 10.20473/fmi.v52i4.5477

Abstract

In the treatment of heart failure is recommended the use of a combination of ACEI (captopril) with diuretics (furosemide), ACEI has the side effect of hyperkalemia 10-38% in hospitalized patients and 10% in outpatients, is increased in patients with renal failure and diabetes mellitus, the use diuretics occur hypokalemia 5-20% in outpatients. Hyperkalemia and hypokalemia both should be avoided in heart failure patients, because it can cause cardiac conduction disorders such as cardiac arrhythmias This study aims to monitor levels of potassium in the use of combination therapy with furosemide captopril in heart failure patients. The study was conducted using the method Prospective Observational Cross Sectional Analysis, conducted in January-May 2015 in heart failure patients male and female NYHA II-III receiving combination therapy with furosemide Captopril met the inclusion criteria were treated in the department CVCU Dr. Wahidin Sudirohusodo Makassar. Potassium levels were measured pre and post administration of the combination therapy. A total of 37 patients met the inclusion and exclusion criteria in this study, 31 male patients (83.8%) and 6 female patients (16.2%) aged between 35-80 years, during this study after administration of the combination therapy, 5 patients (13.5%) had hypokalemia (<3.5 mmol/L) and 2 patients (5.4%) experienced hyperkalemia (> 5 mmol/L) and 30 patients (81.1%) of normal potassium levels (3,5 to 5.0 mmol/L). The test results paired t test p = 0.432 (p> α;α = 0.05) showed no significant differences between potassium levels pre and post potassium levels. In conclusion, the use of a combination of captopril and furosemide therapy, the risk of hyperkalemia and hypokalemia not significant but need to be monitored levels of potassium and ECG patient.