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Journal : Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)

AIR KEMIH (URIN) BEREOSINOFIL DENGAN DUGAAN RADANG SELA GINJAL MENDADAK/NEFRITIS INTERSTISIAL AKUT (NIA) Felly G Sahureka; Fitriani Mangarengi; Uleng Bahrun
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 17, No 1 (2010)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v17i1.1041

Abstract

The diagnosis of AIN is performed by the evaluation of clinical signs and symptoms, laboratory tests, radio imaging and biopsyas a gold standard. In most cases, biopsy wasn't performed because it is invasive for the patients, while the diagnosis is just based onthe clinical sign and symptom, and the immunosuppressive therapy is carried out only after the biopsy. Eosinophyluria found in theAIN patients is the parameter that can be measured non invasively, so that urine eosinophyl test was suggested for the diagnosis/earlydetection of AIN. That background cause us to analyze the urine eosinophyl count in suspected AIN patients. A cross sectional studywas conducted from June to August 2008 on 50 suspect AIN patients and 50 of non AIN at the Laboratory of Clinical Pathology,dr.Wahidin Sudirohusodo Hospital Makassar. Urine eosinophyl test performed by Hansel method, samples were analyzed with SPSSfor Windows version 12.0 using T test and Chi-square test. From 50 suspect AIN patients, they consist of 50% men and 50% womenwith the age distribution between 4 and 72 years old. T test analysis showed that the urine eosinophyl count was higher in suspect AIN(2.820 ± 1.955) compare with the non AIN (0.620 ± 0.923), p < 0.001. The Chi-square test showed that there was a significantrelation between eosinophyluria of the suspect AIN patients. That means there is a significantly relation between eosinphyiluria withthe suspect AIN group, where was found the higher urine eosinophyl compare to those non AIN patients. From this study so far, it canbe suggested that urine eosinophyl test can be used for the diagnosis/early detection of AIN.
KADAR KALIUM DI PACKED RED CELLS SIMPANAN Angeline Sutjianto; Asvin Nurulita; Fitriani Mangarengi
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1083

Abstract

Blood transfusion, is not only transferring the blood cells to the recipient, but also transferring other components such as: glucose,lactate, and potassium. When the blood is stored, many alterations occur in its cmponents, particularly a decrease of adenosine5-triphosphate (ATP) and pH, hemolysis, and an increase of potassium levels as well. One of the transfusion complications that should beavoided is hyperkalemia due to the accumulation of potassium that leaks during the storage. However, hyperkalemia related to transfusiondepends not only on the potassium level in the blood unit, but also on its volume and the rate of its blood administration as well. Theaim of this study was to know the potassium levels in stored Packed Red Cell (PRC). A cohort study was done from May–July 2010. Theresearchers used 48 samples from 16 PRCs derived from 16 donors. The samples were drawn from the of PRC hose’s plasma that had beensealed. The potassium levels were measured on the first day, 10th day, and 20th day of the blood collection. The mean potassium levelon the first day was 3.79 mmol/L, 10th day was 12.22 mmol/L and 20th day was 19.77 mmol/L. Comparison of the potassium levelsbetween the first and 10th day, between first and 20th day, and between 10th and 20th day showed a significant difference (p=0.00). Theincrease of potassium levels in the PRC coincide with the storagetime.
ANGKA BANDING KADAR ASAM URAT AIR KEMIH TERHADAP SERUM DI DIABETES MELITUS TIPE 2 (Ratio of Urinary Uric Acid Levels and Serum Uric Acid in Type 2 Diabetes Mellitus) Amarensi Milka Betaubun; Fitriani Mangarengi; Ruland DN Pakasi
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 21, No 1 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v21i1.1255

Abstract

Diabetes Mellitus (DM) belongs to the group of metabolic diseases. The long-term complications of diabetes such as: diabeticretinopathy, neuropathy, and nephropathy, can be prevented or reduced by controlling the blood glucose levels. Impaired glucose tolerance,hypertension and dyslipidemia can decrease the disappearance from proximal tubules resulting in an increase in serum uric acid. The aimof the study to know the ratio of uric acid urine/serum in DMT2 with controls. This research study used a cross sectional study was andconducted on 35 samples of type 2 diabetes mellitus and 35 control samples of In- and Out-patient Clinics at the Dr. Wahidin SudirohusodoHospital, Makassar. The blood glucose, uric acid levels and urine uric acid were examined by ABX Pentra 400 (colorimetric method). Thenumber of DMT2 male patients was higher than females. Most of their age were between 50−54 years. The ratio of the urinary levels ofurine/serum UA was positively correlated to: age, sex, urine UA in DMT2 and control. Their data were analyzed with unpaired t test (p =0.00). This research showed that the ratio of urine/serum UA in DMT2 was 1.5 times than the controls. The results of this study showedan increase in the ratio of urinary levels of serum uric acid as 1.5 times higher than the controls.