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All Journal Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Journal of Halal Science and Research Journal of Food and Pharmaceutical Sciences
Prita Anggraini Kartika Sari
Universitas Ahmad Dahlan
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Other

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Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
Effect of consumption of vegetables and fruit on nitric oxide levels and T-glutathione levels in type 2 diabetes mellitus patients Prita Anggraini Kartika Sari; Endang Darmawan; Akrom Akrom
Pharmaciana Vol 12, No 2 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.145 KB) | DOI: 10.12928/pharmaciana.v12i2.23322

Abstract

Glutathione is an antioxidant that plays a role in preventing free radicals and reducing oxidative stress, including in patients with type 2 diabetes mellitus (DMT2). One of the factors that affect glutathione status is the individual's ability to produce glutathione and in diabetic patients, T-glutathione levels have decreased. This study aims to determine the effect of fruit and vegetable consumption habits on plasma levels of T-Glutathione. This research method is analytic observational with cross sectional findings, the sample used is 85 subjects in the form of archives of biological materials. Data on habits of consuming vegetables and fruits were collected through interviews, plasma T-GSH levels were determined biochemically using the Elabscience GSH Assay Kit and then analyzed using the Mann Whitney test. The results showed that the average plasma T-GSH levels in patients with the habit of consuming vegetables and fruit and those who did not, were 13.54 ± 3.34 mol/L and 12.73 ± 1.44 mol/L, respectively, but not found a significant difference relationship (p = 0.222). This study provides information that the habit of consuming vegetables and fruit does not provide a significant difference to plasma T-GSH levels in T2DM patients. But these habits still need to be done for health maintenance. Further research is needed that is more specific to the amount and type of certain vegetables and fruits consumed and how to cook them.
The overview of the knowledge level of hypertension prevention and quality of life in Wirobrajan, Yogyakarta Anggara Ersa Putra; Prita Anggraini Kartika Sari; Ginanjar Zukhruf Saputri
Journal of Halal Science and Research Vol. 4 No. 2 (2023): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v4i2.7239

Abstract

Hypertension is a non-communicable disease that is a global problem whose prevalence increases with age. Knowledge is important for a person to evaluate himself. Both hypertension and knowledge can affect a person's quality of life. The purpose of this study was to provide an overview of the level of knowledge about hypertension and the quality of life of the older adults in RW 08 and RW 09 Wirobrajan. The research method used is descriptive-analytic research with inclusion criteria for elderly aged ≥ 60 years. The knowledge test about hypertension and quality of life uses a questionnaire and the EQ-5D3L. The results were 69 older women 67%, education level ≤ 9 years 52%, and history of hypertension 74%. Older adults have a high level of knowledge, with the highest to lowest dimensions being lifestyle (86%), treatment (75%), definition (68%), complications (56%) and adherence to therapy (43%). The EQ5D-3L measurement report showed that the domain scores of no problems with self-care, anxiety/depression, mobility, usual activities, and pain/discomfort were (84.1; 79.7; 73.9; 73.9, and 69.7) %. It was concluded that most of the knowledge and quality of life of the elderly in the Wirobrajan area were in the high category, with the highest domain being self-care and the lowest being pain/discomfort. Further research is needed regarding the relationship between the level of knowledge and the quality of life of older adults. Keywords: Elderly, Hypertension, Knowledge, Quality of life
Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
Co-Authors Akrom, Akrom Anggara Ersa Putra Baiq Maylinda Gemantari Endang Darmawan Putri Rachma Novitasari Saputri, Ginanjar Zukhruf Syarifatul Mufidah