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UJI TOKSISITAS EKSTRAK DAUN HYPERICUM LESCHENAULTII CHOISY DARI GUNUNG LAWU TERHADAP ARTEMIA SALINA L. SEBAGAI KANDIDAT ANTIKANKER Yudha Noviana; Dwimei Ayudewandari Pranatami
At-Taqaddum Volume 11, Nomor 2, Tahun 2019
Publisher : Quality Assurance Institute (LPM) State Islamic University Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/at.v11i2.4448

Abstract

Mount Lawu is a biodiversity rich mountain, with the potensial of medicinal plants of various kinds including anticancer plants. Flora on the Mount Lawu that has potential for anticancer is Hypericum leschenaultii Choisy containing compounds hypericin. Hypericum has several biological activities such as a antioxidant, antitumor, and anticancer. The research aims to determine the potential of bioactive compounds and extracts of the leaves of H. leschenaultii from Mount Lawu and toxicity to Artemia salina Leach and profile Thin Layer Chromatography (TLC) it.   Ethanol extract of the leaves of H. leschenaultii was tested toxicity with Brine Shrimp Lethality Test (BST) using a concentration of  400 µg/ml, 200 µg/ml, 100 µg/ml, 50 µg/ml, 25 µg/ml. The TLC profiles of bioactive compounds were determined by using spesific spray reagent.  The results show the potential and toxicity of leaf extract of H. leschenaultii with LC values 175,77 µg/ml. TLC profile of bioactive compounds leaf extract of H. leschenaultiicontaining flavonoids with Rf values of 0,98 and terpenoid compounds with Rf value of 0,91; 0,95; 0,98. ==================================================Gunung Lawu merupakan gunung yang kaya akan keanekaragaman hayati,  dengan potensi tumbuhan obat yang beragam, termasuk potensi tumbuhan sebagai antikanker.  Adanya potensi tumbuhan sebagai sumber senyawa antikanker tersebut belum banyak diteliti dan digunakan sebagai pengobatan alternatif.  Flora di Gunung Lawu yang potensial sebagai tumbuhan antikanker, yaitu Hypericum leschenaultii Choisy yang mengandung senyawa hypericin dan memiliki status keberadaan yang melimpah di Gunung lawu, sehingga sangat penting untuk diketahui manfaatnya agar dapat dimanfaatkan lebih luas.  Hypericin memiliki beberapa aktivitas biologis seperti antioksidan, antitumor, dan antikanker. Penelitian ini bertujuan untuk mengetahui potensi senyawa bioaktif ekstrak daun H. leschenaultii dari Gunung Lawu sebagai antikanker dengan melihat toksisitasnya terhadap Artemia salina Leach serta profil Kromatografi Lapis Tipis (KLT) nya. Untuk mengetahui potensi sebagai tanaman antikanker maka ekstrak etanol daun H. leschenaultii diuji toksisitasnya dengan metode Brine Shrimp Lethality Test (BST). Dalam uji BST tersebut digunakan 5 konsentrasi esktrak etanol daun H. leschenaultii yaitu: 400 µg/ml, 200 µg/ml, 100 µg/ml, 50 µg/ml, 25 µg/ml. Kandungan senyawa bioaktif dideteksi dengan reagen semprot spesifik untuk mengetahui profil KLT-nya. Hasil penelitian menunjukkan potensi dan toksisitas ekstrak H. leschenaultii dengan nilai LC 175,77 µg/ml. Profil KLT senyawa bioaktif ekstrak daun H. leschenaultii mengandung senyawa flavonoid dengan nilai Rf 0,98 serta senyawa terpenoid dengan nilai Rf 0,91; 0,95; 0,98. 
INDEKS KEPUASAN MAHASISWA TERHADAP LAYANAN AKADEMIK DAN NON AKADEMIK UIN WALISONGO SEMARANG Anila Umriana; Dwimei Ayudewandari Pranatami
Jurnal Penjaminan Mutu Vol 8 No 1 (2022)
Publisher : UHN IGB Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (817.786 KB) | DOI: 10.25078/jpm.v8i1.767

Abstract

Higher education as one of the places where education is held is expected to always maintain its quality and quality. To see the quality or quality of higher education management can be assessed from two indicators, namely the fulfillment of quality standards and the achievement of customer satisfaction. Universities must be able to manage their service quality system and administration because if not, the trust of higher education users will decrease as well as the quality of students as one of the university's users, so that student satisfaction measurements need to be carried out regularly to be input and improvement for the university. Student satisfaction survey was conducted on aspects of academic and non-academic services at UIN Walisongo Semarang. Academic and academic service aspects are each measured by 8 indicators. This study aims to determine the level of student satisfaction with service quality after participating in the learning process at UIN Walisongo Semarang. This study uses a quantitative approach and survey methods. The population of this survey is all students of UIN Walisongo Semarang. The results of the assessment of the student satisfaction index on academic services are as follows: the highest satisfaction is on the online guardianship indicator with an index of 2.99 and the lowest satisfaction is on the online lecture system (E-learning) indicator with an index of 2.27. Meanwhile, the results of the satisfaction index assessment on non-academic services are as follows: the highest indicators are; Religious guidance services for students (3.01), while the lowest index is; Career guidance and job information services (Walisongo Career Center) (2.69). All satisfaction results show high satisfaction criteria.
Education Power Satisfaction Index on UIN Walisongo Semarang Services Dwimei Ayudewandari Pranatami; Anila Umriana Umriana; Eka Vasia Anggis
Journal of Quality Assurance in Islamic Education (JQAIE) Vol 1 No 1 (2021): January - June
Publisher : Institut Agama Islam Negeri Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.428 KB) | DOI: 10.47945/jqaie.v1i1.390

Abstract

Quality assurance is one of the benchmarks that can be seen in assessing the quality of a university. All efforts that can be made related to the quality assurance process must be carried out starting from the level of study programs to tertiary institutions and a thorough evaluation not only related to the learning curriculum but also the human resources involved in it. One of the essential human resources involved in the learning process is educators. The optimal performance of educators will affect the whole teaching and learning process, and the implementation of these educators is strongly influenced by satisfaction with campus services. So, this study aims to analyze the satisfaction of education personnel with the services provided by the campus. Surveying educators carried out the data search process in the UIN Walisongo Semarang. Nine aspects are analyzed by the level of satisfaction by educators, namely 1) Recruitment and Selection, 2) Employee Orientation and Placement, 3) Training, Learning and Development Tasks, 4) Job Evaluation 5) Career Paths 6) Welfare 7) Attendance and Assignment System, 8) Termination and 9) Campus Facilities. The results of the analysis obtained are that the satisfaction of education personnel is at a moderate to a very high level with the aspect that shows the highest satisfaction in the achievement and assignment system variable (3.50) and the element that is at the lowest level of satisfaction is the welfare variable (3.14).
PENGUATAN KARAKTER ANAK: PERILAKU MEMILAH SAMPAH DAN KETELADANAN AKHLAK NABI Ndzani Latifatur Rofi'ah; Dwimei Ayudewandari Pranatami; Hafidha Asni Akmalia; Dian Tauhidah
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 3 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i3.1152-1160

Abstract

Sampah masih menjadi masalah bagi masyarakat di Indonesia. Perilaku memilah sampah menjadi salah satu alternatif solusi yang dapat diterapkan untuk mengurangi dampak masalah sampah terutama sampah plastik. Usia anak menjadi usia optimal untuk melatihkan karakter menjaga lingkungan, melalui perilaku memilah sampah. Penguatan karatkter dapat didukung dengan meneladani akhlak nabi dalam kehidupan sehari-hari. Pengabdian ini dilakukan dengan tujuan untuk menguatkan karakter anak melalui perilaku memilah sampah dan keteladanan sifat nabi. Kegiatan dilakukan dengan metode bermain dan belajar dengan teknik ceramah (penyampaian materi), menonton video, dan permainan. Hasil kegiatan dapat memberikan wawasan kepada anak-anak terkait dengan kegiatan pelestarian lingkungan melalui pemilahan sampah dan pembentukan karakter meneladani sifat nabi. Kegiatan berjalan dengan lancar, peserta mengikuti dengan antusias dan lebih memahami pentingnya menerapkan perilaku memilah sampah dengan diimbangi meneladani sifat nabi. Kegiatan serupa perlu dilakukan kembali hingga anak-anak dapat menerapkan pemahaman mereka dalam kehidupan sehari-hari.