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Hexanto Muhartomo
Departement Of Neurology, Faculty Of Medicine, Universitas Diponegoro Semarang Indonesia
Medicine & Pharmacology

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The Effect of Mat Pilates exercise on Sleep Quality of Obese Young Adults Maria Devina Putri Elvariani; Rahmi Isma Asmara Putri; Erna Setiawati; Hexanto Muhartomo
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 3 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i3.29718

Abstract

Background: Obesity currently becomes one of the world's problems that can decrease a person’s quality of sleep. Pilates exercise was found to improve sleep quality in obese patients. Pilates exercise are safe to do because they don't involve jumping and running so they avoid trauma. Mat Pilates exercise is basic exercises that are done on the floor on a mat with simpler movements.Objective: To analyze sleep quality in obese young adults before doing Mat Pilates exercise and to compare changes in sleep quality for obese young adults before and after doing Mat Pilates exercise.Methods: This study used a quasi-experimental design applying one group pre-posttest. Samples were taken by purposive sampling with a total of 36 people who met the inclusion and exclusion criteria. The measurement of sleep quality used the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Data analysis was tested for normality by using the Shapiro-Wilk test and the effect of Mat Pilates exercise on sleep quality in the treatment group using the Wilcoxon test. The difference is significant if p <0.05.Results: The average sleep quality for young adults before participating in the Mat Pilates exercise was 8.22 ± 1.87, while the average sleep quality for young adults after participating in the Mat Pilates exercise was 4.33 ± 0.77. The statistical test results showed that there was a significant difference (p = <0.001).Conclusion: There is an improvement in the mean value of sleep quality after doing Mat Pilates exercise.  
THE CORRELATION OF LONG-TERM COMBINATION TREATMENT OF VALPROIC ACID AND TOPIRAMATE ON SERUM VITAMIN D LEVELS AMONG CHILDREN WITH EPILEPSY Hexanto Muhartomo; M.I Widiastuti; Endang Kustiowati; Aris Catur Bintoro; Arinta Puspita Wati; Alifiani Hikmah Putranti; Rony Parlindungan Sinaga
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 1 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i1.32563

Abstract

Background: Epilepsy is a chronic condition characterized by unprovoked seizure. Vitamin D is necessary in child development process and is strongly influenced by the presence of anti-epileptic drugs.Objective: To determine the correlation of treatment duration and serum vitamin D levels in children with epilepsy who use the combination of valproic acid and topiramateMethods: A cross sectional study among forty pediatric patients with epilepsy with age range of 5-10 years at Dr. Kariadi Hospital Semarang. Examination of serum vitamin D levels is done by ELISA. Statistical analysis using Spearman correlation test and partial correlation test with significance level p = 0.05.Results: The mean of serum vitamin D levels in patient with combination treatment after 24 months was 21.87±1.21ng/ml, in those who still having seizure was 27.94±2.40ng/ml, and among who received delayed therapy was 23.23±2.07ng/ml. Bivariate analysis depicted that there was negative correlation between duration of treatment (rho= -0.850, p<0.001), onset of therapy (rho=0.604, p<0.001) and seizure frequency (rho=0.559, p<0.001) with serum vitamin D levels. Partial correlation analysis showed a significant correlation between duration of treatment and serum vitamin D levels after adjusted by onset of therapy (rho=-0.839, p<0.001) and seizure frequency (rho=-0.856, p<0.001).Conclusion: There is a correlation between the duration of treatment and serum vitamin D levels among children with epilepsy
Relationship Between Frequency Of Tension Type Headache (TTH) In Epilepsy With Cognitive Function Diah Patlika; Herlina Suryawati; M.I. Widiastuti; Endang Kustiowati; Hexanto Muhartomo; Arinta Puspita Wati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 2 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i2.32620

Abstract

Background : Epilepsy is a chronic disease that increases the risk of interictal headaches, one of which is tension type headache (TTH). TTH in epilepsy is triggered by recurrent neurogenic inflammation and central sensitization leading to pericranial tenderness. Recurrent neurogenic inflammation can affect cognitive function. The frequency of TTH in epilepsy is thought to be related to cognitive function score.Objective : Analyzing the relationship between the category of TTH frequency, onset of epilepsy, seizure frequency, age and education with cognitive score.Methods : Our study is an analytic observational study with a cross sectional design that took place from April to September 2021. The subjects of the study were epilepsy patients suffering from TTH at Dr. Kariadi Hospital, Semarang who met the inclusion and exclusion criteria. Patients’s data was obtained by filling out a questionnaire form. Assessment of the category of TTH frequency used ICHD-3 beta 2013 criteria. Assessment of cognitive function used the MoCA-Ina score. Data was analyze with Spearman correlation test, the results were significant if the p value <0.05.Results : Forty one epilepsy patients consist of 14 infrequent episodic TTH, 14 frequent episodic TTH and 13 chronic TTH. There was significant relationship between the MoCA-Ina score and the TTH frequency category (r=0,362; p=0,02), and education level (r=0,493; p=0,001). There was a weak relationship between the MoCA-Ina score and the onset of epilepsy or seizure frequency, while there was no relationship with age.Conclusion : There was a moderate relationship between the TTH frequency in epilepsy with cognitive function. Keywords : epilepsy, tension type headache (TTH), Montreal Cognitive Assesment -  Indonesian version (MoCA-Ina)
Correlation between Interleukin 10 Serum Levels and Severity of Peripheral Neuropathy in Multibacillary Leprosy Patients a Research Article Fajar Sekti Reliyana; Hexanto Muhartomo; Endang Kustiowati; Yosep Ferdinand Rahmat Sugiyanto; Retnaningsih Retnaningsih; Arinta Puspita Wati; Rahmi Ardhini; Aditya Kurnianto
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 2 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i2.32648

Abstract

ABSTRACT  Background of the ResearchLeprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. Clinical presentations of leprosy neuropathy are obtained when the nerve damage is more than 30% of peripheral nerve fibers. The anti-inflammatory property of interleukin 10 is supposed to protect tissue from the damage caused by proinflammatory cytokines. Instead, it causes extensive nerve damage due to suppression of the cellular immune system, failure of forming granuloma to limit the growth of Mycobacterium leprae. As a result, it multiplies and spreads. Purpose of the ResearchThe purpose of the research is to analyze the correlation between interleukin levels 10 serum and the severity of peripheral neuropathy. Methods of the ResearchThe method used is cross-sectional research on 30 subjects with multibacillary leprosy aged 18-65 at the Neurology Department of Kelet Hospital Jepara from September to October 2021. The questionnaire was used to collect data of the patients. Interleukin level 10 serum evaluation is assessed by examining blood serum. Data analysis used Spearman Correlation Test. The significant result occurs if it is p<0.05. Research resultPatients with multibacillary leprosy are mostly men (73.3%). There is also a strong significant correlation between interleukin 10 levels and the severity of peripheral neuropathy (p<0.001) with rho (0.7) ConclusionThere is a strong and significant correlation between serum interleukin 10 levels and the severity of peripheral neuropathy in multibacillary leprosy Keywords: multibacillary leprosy, interleukin 10, peripheral neuropathy
KNOWLEDGE OF GENERAL DOCTORS OF PRIMARY HEALTH SERVICE FACILITIES IN SEMARANG CITY ABOUT DEMENTIA IN SEMARANG CITY Arinta Puspita Wati; Hexanto Muhartomo; Fatiha Sri Utami Tamad; Retna Putri
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 4 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i3.33250

Abstract

Background. Dementia is a syndrome due to brain disease, usually chronic or progressive and there is a disturbance of sublime function. Lack of knowledge and awareness of health workers about the occurrence of dementia can worsen dementia due to delays in diagnosis and treatment. Method. This study is a descriptive study with a cross sectional design involving 66 respondents who have agreed to the informed consent and are general practitioners who work in Primary Health Care Facilities. Sampling using consecutive sampling technique, samples that meet the inclusion and exclusion criteria. Data collection was carried out in November 2021. Data analysis used SPSS 22.0 ver. Results. The average knowledge of respondents before the training was described from the pretest score of 5.2. Conclusion. Lack of knowledge about dementia in general practitioners who work in primary health care facilities in the Semarang.
Co-Authors Aditya Kurnianto Alifiani Hikmah Putranti Arinta Puspita Wati Aris Catur Bintoro Diah Patlika Endang Kustiowati Endang Kustiowati Endang Kustiowati Erna Setiawati Fajar Sekti Reliyana Fatiha Sri Utami Tamad Herlina Suryawati M.I Widiastuti M.I. Widiastuti Maria Devina Putri Elvariani Rahmi Ardhini Rahmi Isma Asmara Putri Retna Putri Retnaningsih Retnaningsih Rony Parlindungan Sinaga Yosep Ferdinand Rahmat Sugiyanto