ABSTRAKTingkat pengetahuan penderita tuberculosis paru akan mempengaruhi mekanisme koping yang digunakan penderita tuberculosis paru dalam menghadapi penyakitnya. Tujuan penelitian untuk mengetahui hubungan tingkat pengetahuan dengan mekanisme koping penderita tuberculosis paru di wilayah kerja Puskesmas Guntung Payung dan Puskesmas Banjarbaru. Studi ini menggunakan desain deskriptif analitik dengan pendekatan cross sectional. Penelitian ini dilakukan pada Juni-Juli 2012 dengan jumlah sampel sebanyak 30 responden. Hasil penelitian menunjukkan bahwa tingkat pengetahuan pasien tentang tuberculosis paru dengan kategori tinggi 83,3%, sedang 16,7% dan rendah 0 %, mekanisme koping sebanyak 100% responden dalam kategori mekanisme koping adaptif. Hasil analisis bivariat menggunakan uji statistik spearman diperoleh nilai p = 0,008 dan koefisien korelasi spearman (r) = 0,475 dengan arah korelasi positif (p<0.05). Terdapat hubungan bermakna antara tingkat pengetahuan tentang tubercuosis paru dengan mekanisme koping penderita tuberculosis paru.Kata-kata kunci: mekanisme koping, penderita tuberculosis paru, tingkat pengetahuanABSTRACTLevel of knowledge patients with pulmonary tuberculosis would be affected the coping mechanisms that are used in dealing of patients with pulmonary tuberculosis disease. The aim of this research was to determine the correlation between level knowledge of pulmonary tuberculosis patients and coping mechanism patients with pulmonary tuberculosis in work area Guntung Payung and Banjarbaru public health center. This research used an analytical descriptive study which using cross sectional approach method. It has been done on June-July 2012 with 30 respondents as the sample. The result of this research showed that 83% of the respondents are the high level in tuberculosis knowledge category, 16,7% are the middle level and 0 % in low level. Coping mechanism is 100% of the respondents in the categorizes as adaptive coping mechanism. Analysis of bivariate correlation used spearman statistic test, value of p=0,008 and spearman coefficient correlation ( r )= 0,475 with the direction of the positive correlation ( p<0,05). There is high correlation between pulmonary tuberculosis patients level knowledge about pulmonary tuberculosis and pulmonary tuberculosis patients coping mechanism. Keywords: coping mechanism, level of knowledge, pulmonary tuberculosis patient