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All Journal Majalah Kedokteran Bandung Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Berkala Ilmu Kesehatan Kulit dan Kelamin Molecular and Cellular Biomedical Sciences (MCBS) SCRIPTA SCORE Scientific Medical Journal
Deryne Anggia Paramita
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Sumatera Utara, Medan
Biochemistry, Genetics & Molecular Biology Dentistry Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

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Zinc Plasma Levels in Recurrent Vulvovaginal Candidiasis Patients Deryne Anggia Paramita; Kristina Nadeak; Richard Hutapea
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 1 (2017): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.461 KB) | DOI: 10.20473/bikk.V29.1.2017.16-20

Abstract

Background: Recurrent vulvovaginal candidiasis (RVVC) is episodes of thrush vulvovaginalis 4 times or more within 12 months.  Some exogenous pathogenic factors and host are known to be associated with RVVC including sex hormones, contraceptives, obesity, cellular immune responsses which could influenced by zinc. Purpose: To compare differences between plasma zinc levels of RVVC patients with controls. Methods: The study was cross involving 30 people with RVVC and 30 controls. Each study subjects vaginal smear examination and blood examination to measure the levels of zinc. Results: Mean value of plasma zinc levels in the case group (22.85 цg/dL) was lower than the control group (22.96 цg/dL). However, this difference was not statistically significant (p = 0.270). Conclusion: There is no difference between the plasma zinc level of vulvovaginalis recurrent candidiasis patients with controls.
Susbstance P Levels in Children with Atopic Dermatitis Khairina Nasution; Deryne Anggia Paramita; Nova Zairina Lubis
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.182-186

Abstract

Background: Atopic dermatitis (AD) is the most common skin disease in infants and children. AD is influenced by hereditary and environmental factors, and it is characterized by an inflammatory reaction in the skin. In developing countries, children suffering from AD are estimated around 10–20%, of which 60% of the cases persist into adulthood. Substance P is a cutaneous neuropeptide that contributes to the pathogenesis of AD. Substance P promotes the production of nerve growth factors from keratinocytes, and the release of histamine, leukotriene, or tumor necrosis factor from mast cells, which cause the growth of sensory nerve fibers, augmentation of skin inflammation, and are considered pruritogenic factors. Purpose: This study aims to determine the description of substance P in children with atopic dermatitis using a descriptive observational study with a cross-sectional approach. Methods: This is a destructive observational study with a crossectional approach samples were selected from AD patients at the Universitas Sumatera Utara Hospital. Result: The largest group of subjects were childhood (2–12 years old), there was 60%, followed by the adolescent group (12–18 years old) and the infant group (<2 years old). In the childhood group, the highest level of substance P was found in girls with a mean of 349.03 ± 146.7. On the other hand, the highest levels of substance P in the adolescent were found in males with a mean of 243.73 ± 64.57 ng/L. Conclusion: In this study, we found that the level of substance p was higher in the childhood group.
Co-Authors Anyelin Sriwulan Dina Arwina Dalimunthe Fauzan Azmi Hasti Habibi Samosir Khairina Nasution Kristina Muhammad Ikhfa Yusril Bahari Nova Zairina Lubis Puteri Wulandari Richard Hutapea Sry Suryani Widjaja Syahril Rahmat Lubis