Andrianto
Department Of Cardiology And Vascular Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya

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Journal : Folia Medica Indonesiana

THE DIFFERENCE OF BLOOD PRESSURE AND ARTERIAL STIFFNESS AFTER INTAKE OF ARABICA AND ROBUSTA COFFEE IN CONTROLLED HYPERTENSION Budi S Pikir; Andrianto Andrianto; Ford Ance A
Folia Medica Indonesiana Vol. 53 No. 3 (2017): September 2017
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.611 KB) | DOI: 10.20473/fmi.v53i3.6457

Abstract

Potential mechanisms of caffeine promote large artery stiffness and associated with increased morbidity and mortality of cardiovascular disease. To find the difference of blood pressure and arterial stiffness after intake of arabica and robusta coffee in controlled hypertension, a quasi-experimental study was done enrolling 24 controlled hypertension and 24 normotensive subjects collected by purposive sampling. Subjects received ± 10,6 g caffeinated coffee in 150 ml water with crossover protocol twice in 5 days. The assessment of arterial stiffness by obtaining ultrasound 2D image of common carotid artery then was calculated with beta stiffness index. Blood pressure and arterial stiffness was measured before coffee intake and again at 30 to 60 minutes thereafter. In controlled hypertension, significant differences were found between initial systolic blood pressure (SBP), 30 and 60 minutes after arabica (p 0,002) and robusta (p 0,012) intake; between diastolic blood pressure (DBP), 30 and 60 minutes after of arabica (p 0,004) and robusta (p 0,025) oral administration; and between initial beta stiffness index, 30 and 60 minutes after arabica (p 0,018) oral administration. However, no significant difference was found between initial beta stiffness index, 30 and 60 minutes after robusta (p 0,104) oral administration. No significant difference was found in all variables after arabica and robusta intake. Significant differences were found in blood pressure after arabica or robusta intake and in arterial stiffness after arabica intake. However, no significant differences were found in arterial stiffness after robusta intake and in all variables after arabica and robusta intake.
Mortality among Heart Failure Patients in the Presence of Cachexia Andrianto; Ula Nur Pramesti Karman; Sony Wibisono Mudjanarko; Meity Ardiana; Hanestya Oky Hermawan
Folia Medica Indonesiana Vol. 59 No. 1 (2023): March
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (564.741 KB) | DOI: 10.20473/fmi.v59i1.39512

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Highlights: Around 38.8% of heart failure patients with cachexia died during the 180-1,876-day follow-up period. Cachexia increases the risk of mortality in heart failure patients. Abstract: Despite the fact that obesity has long been recognized as a risk factor for cardiovascular disease, the mortality rate of heart failure (HF) patients with cachexia is still high. Several studies have been conducted to investigate the association between cachexia and mortality in HF patients. However, the research results vary, as do the diagnostic criteria employed to assess cachexia. This meta-analysis aimed to conclusively summarize the association between cachexia and mortality in HF patients. The data were obtained from prospective or retrospective cohort studies with full texts in English or Indonesian and keywords related to "cachexia," "heart failure," and/ or "mortality". Studies that did not assess mortality in HF patients with cachexia and had no full text accessible were omitted. A literature search was conducted through four databases (PubMed, Web of Science, Scopus, and SAGE Journals) using keywords, reference searches, and/ or other methods on April 2022 in accordance with the Preferred Reported Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data from the selected studies were presented and analyzed using qualitative and quantitative synthesis methods. The Newcastle-Ottawa Scale (NOS) was used to assess the risk of bias in the selected cohort studies. The qualitative synthesis contained nine studies, whereas the quantitative synthesis (meta-analysis) included six studies. Cachexia was found in 16.0% of the 4,697 patients studied. During the 180-1,876-day follow-up period, 33.0% of the patients died, with a mortality rate of 38.8% among the patients with cachexia. The pooled analysis revealed cachexia to be a significant predictor of mortality in HF patients (hazard ratio (HR)=3.84; 95% CI=2.28-6.45; p<0.00001), but with significant heterogeneity (p<0.00001; I2=88%). In conclusion, cachexia worsens HF prognosis.