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All Journal International Journal of Public Health Science (IJPHS) Dental Journal (Majalah Kedokteran Gigi) Indonesian Journal of Chemistry
Rosyida, Niswati Fathmah
Department Of Orthodontics, Faculty Of Dentistry, Universitas Gadjah Mada, Yogyakarta - Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions

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The effect of silanated and impregnated fiber on the tensile strength of E-glass fiber reinforced composite retainer Niswati Fathmah Rosyida; Siti Sunarintyas; Pinandi Sri Pudyani
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 1 (2015): March 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.65 KB) | DOI: 10.20473/j.djmkg.v48.i1.p22-25

Abstract

Background: Fiber reinforced composite (FRC) is can be used in dentistry as an orthodontic retainer. FRC  still has a limitations because of to  a weak bonding between fibers and matrix. Purpose: This research was aimed to evaluate the effect of silane as coupling agent and fiber impregnation on the tensile strength of E-glass FRC. Methods: The samples of this research were classified into two groups each of which consisted of three subgroups, namely the impregnated fiber group (original, 1x addition of silane, 2x addition of silane) and the non-impregnated fiber group (original, 1x addition of silane, 2x addition of silane). The tensile strength was measured by a universal testing machine. The averages of the tensile strength in all groups then were compared by using Kruskal Wallis and Mann Whitney post hoc tests. Results: The averages of the tensile strength (MPa) in the impregnated fiber group can be known as follow; original impregnated fiber (26.60±0.51), 1x addition of silane (43.38±4.42), and 2x addition of silane (36.22±7.23). The averages of tensile strength (MPa) in the non-impregnated fiber group can also be known as follow; original non-impregnated fiber (29.38±1.08), 1x addition of silane (29.38±1.08), 2x addition of silane (12.48±2.37). Kruskal Wallis test showed that there was a significant difference between the impregnated fiber group and the non-impregnated fiber group (p<0.05). Based on the results of post hoc test, it is also known that the addition of silane in the impregnated fiber group had a significant effect on the increasing of the tensile strength of E-glass FRC (p<0.05), while the addition of silane in the non-impregnated fiber group had a significant effect on the decreasing of the tensile strength of E-glass FRC. Conclusion: It can be concluded that the addition of silane in the non-silanated fiber group can increase the tensile strength of E-glass FRC, but the addition of silane in the silanated fiber group can decrease the tensile strength of E-glass FRC. It is also known that the impregnation of fiber can increase the tensile strength of E-glass FRC.
Solubility Enhancement of Simvastatin through Surfactant Addition for Development of Hydrophobic Drug-Loaded Gelatin Hydrogel Niswati Fathmah Rosyida; Pinandi Sri Pudyani; Akhmad Kharis Nugroho; Ika Dewi Ana; Teguh Ariyanto
Indonesian Journal of Chemistry Vol 19, No 4 (2019)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.913 KB) | DOI: 10.22146/ijc.38153

Abstract

This study aims to synthesize simvastatin hydrogel as drug delivery system with surfactant addition for improving solubility of simvastatin. Surfactants used in the study were the zwitterionic amino acid of arginine and nonionic surface-active agent of polysorbate 80. The solubility study was conducted by pouring of an excess mass of simvastatin into the solution of a surfactant in a conical flask. The sample was shaken up to 72 h in a mechanical water bath shaker at a varied temperature of 25, 40, and 50 °C. The amount of drug dissolved in solution was analyzed by UV/Visible spectrophotometer at 238 nm. The results showed that the simvastatin solubility is profoundly influenced by the surfactant type, surfactant concentration, and temperature. Polysorbate 80 exhibited as a better surfactant than arginine and an enhancement up to 1400 times, in respect of without any addition of a surfactant, was observed. Based on the solubility study, simvastatin-loaded gelatin hydrogel composite was formulated and the characterization (FTIR and SEM) showed the successful impregnation. The hydrogel microparticles of featured swelling indexes in the range of 2–6 for every patch and presented a sustained release profile.
Does mouthwash degrade the force of orthodontic latex elastics? Ananto Ali Alhasyimi; Sri Suparwitri; Niswati Fathmah Rosyida
International Journal of Public Health Science (IJPHS) Vol 11, No 4: December 2022
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v11i4.21923

Abstract

With the surge of COVID-19 pandemic, orthodontists have recommended the use of mouthwashes. However, this product often includes substances that change the pH of the oral environment and potentially alter orthodontic elastic force. This study aimed to investigate the effect of several mouthwashes on the force decay of latex elastics. A total of 100 orthodontic latex elastics (1/4”) were separated into five groups: control, zinc sulfate 0.2%, chlorhexidine 0.2%, sodium fluoride 0.2%, and povidone–iodine 1%. The samples were all stretched to 19.05 mm, stored in artificial saliva solutions, and housed in an incubator. Every 12 hours, the specimens from groups 2–5 were immersed in the test mouthwashes for 60 seconds and immediately returned to the artificial saliva. A tension gauge with five times that of the activation was used to measure force. Elastic force was tested at five-time intervals: baseline, 1, 6, 12 and 24 hours. Statistical analysis was conducted using two-way ANOVA and Tukey post hoc test. Results showed statistical differences for the time intervals and force degradation of orthodontic latex elastics (P<0.05). The majority of force loss occurred within 6 hours of extension and immersion. Mouthwashes had no influence on the reduction in elastic force (P>0.05). The force degradation of orthodontic latex elastics was unaffected by mouthwashes. The lowest force degradation was generated by povidone–iodine, followed by zinc sulfate, sodium fluoride, and chlorhexidine.
Co-Authors Akhmad Kharis Nugroho Ananto Ali Alhasyimi Ika Dewi Ana Pinandi Sri Pudyani Siti Sunarintyas Sri Suparwitri Teguh Ariyanto