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Journal : Indonesian Applied Physics Letters

3D Printing Geometric Scaffold Design Variation of Injectable Bone Substitutes (IBS) Pa Dyah Hikmawati; Sarda Nugraheni; Aminatun Aminatun
Indonesian Applied Physics Letters Vol. 1 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v1i2.23447

Abstract

3D printing technology application in tissue engineering could be provided by designing geometrical scaffold architecture which also functionates as drug delivery. For drug delivery scaffold on bone tuberculosis, the cell pore of the geometric design was filled with Injectable Bone Substitutes (IBS) which had streptomycin as anti-tuberculosis. In this study, scaffolds were synthesized in three cells geometric filled by Injectable Bone Substitutes (IBS), Hexahedron, Truccated Hexahedron, and Rhombicuboctahedron, which had 2.5 mm x 2.5 mm x 2.5 mm size dimension and 0.8 mm strut. The final design was printed in 3D with polylactic acid (PLA) filament using the FDM process (Fused Deposition Modelling). The composition of IBS paste was a mixture of hydroxyapatite (HA) and gelatine (GEL) 20% w/v with a ratio of 60:40, streptomycin 10 wt% and hydroxypropyl methylcellulose (HPMC) 4% w/v. It was then characterized using Fourier-transform infrared spectroscopy (FTIR). Scaffold–paste characterization was included pore size test of 3D printing result before and after injected using Scanning Electron Microscope SEM, porosity test, and compressive strength test. The result showed that the pore of scaffold design was 1379 µm and after injected with IBS paste, the pore leaving 231.04 µm of size. The scaffold with IBS paste porosity test showed ranges between 40,78-70,04% while the compressive strength of before and after injected ranges between 1,110-634 MPa and 2,217-6,971 MPa respectively. From the test results, the scaffold 3D printing with IBS paste in this study had suitable physical characteristics to be applicated on cancellous bones which were infected by tuberculosis.
MECHANICAL CHARACTERISTIC STUDY OF COBALT ALLOY PREPARED BY POWDER METALLURGY METHOD Aminatun Aminatun; Jan Ady; Mega Farynda KD
Indonesian Applied Physics Letters Vol. 1 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v1i2.23448

Abstract

This study was conducted to determine the effect of compaction pressure and sintering temperature variations on the properties of physical, mechanical, and micro cobalt alloy. Manufacture of the cobalt alloy with compositions 63,75%, chromium 30%, molybdenum 5%, manganese 0,5%, silicon 0,5%, and 0,25% nitrogen using powder metallurgy method. Variations of compaction pressure were 339,70 MPa, 396,31 MPa, dan 452,93 MPa, and sintered at temperature 12000C and 130 0C for 2 hours of holding time. Density was increased along with the increasing compaction pressure and sintering temperature (3,9-6,6 g/cm). The hardness was also increased along with the increasing compaction pressure and sintering temperature  205,1-316,2 VHN. XRD results showed that γ phase with fcc structure was formed at the temperature of 12000C and 13000C for all variations of pressure. SEM-EDX results showed that the oxygen content decreased along with increasing compaction pressure and sintering temperature. Based on ASTM F75 hardness standard, the sample with compaction pressure 452,93 MPa and sintered at 13000C was the best cobalt alloy with a hardness value of 316.2 VHN.