Mufidatul Asmi
Study Program of Veterinary Medicine, Faculty of Medicine, Hasanuddin University

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Correlation Between Female Ovariohysterectomy and Male Orchiectomy Rats With Blood Cholesterol Levels dian fatmawati fatmawati; Mufidatul Asmi; Ilham Akbar Rahman; Irfan Idris; Dwi Kesuma Sari
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 5 No. 1, JANUARY 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v5i1.12122

Abstract

Currently, sterilization is the main choice for controlling the population of pets. But sterilization also has long-term effects. One of them is related to cholesterol levels in the blood. In this study, we investigated the effect of castration on changes in cholesterol levels. Twenty-three Wistar rats aged 10 weeks were divided into four groups: the female sham surgery group (n = 6) and the male sham surgery group (n = 6) who underwent sham surgery, the orchiectomized (OCX) group (n = 6), which underwent bilateral OCX at 10 weeks of age, the ovariectomy (OVX) group of mice (n = 6) who underwent bilateral OVX at 10 weeks of age. At 8 weeks postoperatively, all 23 mice were shut off. The serum cholesterol level is measured. Serum cholesterol levels had no effect 0.168, namely (p value> 0.05) in the castration rat group (OCX + OVX) compared to the sham surgery group with 67.08 ± 13.581 and 76.00 ± 16.346, respectively. Our findings indicate that orchiectomy and ovariectomy have no effect on cholesterol levels.