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Iqbal Musthapa
Kelompok Penelitian Kimia Organik Bahan Alam, Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Teknologi Bandung, Jalan Ganeca 10, Bandung 40132
Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

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Bergenin, Suatu Dihidroisokumarin dari Kayu dan Kulit Batang Shorea Stenoptera Burck§ Euis Holisotan Hakim; Rudiyansyah Rudiyansyah; Iqbal Musthapa; Koichi Takeya
Journal of Mathematical and Fundamental Sciences Vol. 35 No. 2 (2003)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/itbj.sci.2003.35.2.1

Abstract

Bergenin, a dihydroisocoumarin derivative of glucopyranosyl gallic acid had been isolated for the first time from ethyl acetate extracts of the heartwood and tree bark, together with (-)-α-viniferin from the tree bark of Shorea stenoptera. The structure of bergenin was elucidated based on analysis of spectroscopic data UV, IR, MS, 1H and 13C NMR. Bergenin showed weak cytotoxic activity against murine leukemia P-388 cells (IC50 >100 μg/mL), and also weak toxicity against Artemia salina shrimps (LC50 >500 μg/mL).
Co-Authors Euis Holisotan Hakim Koichi Takeya Rudiyansyah Rudiyansyah