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Hubungan Hipertensi dengan Mortalitas Pasien Covid-19 di Tangerang Selatan Choirunnisa Choirunnisa; Helda Helda
Jurnal Epidemiologi Kesehatan Indonesia Vol 5, No 2 (2021)
Publisher : Department of Epidemiology, FoPH, UI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.7454/epidkes.v5i2.5265

Abstract

Covid-19 (Coronavirus Disease-2019) adalah penyakit yang disebabkan oleh virus SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2). Usia tua (≥65 tahun), jenis kelamin laki-laki, hipertensi, penyakit kardiovaskular, diabetes, PPOK dan kanker dapat meningkatkan risiko kematian akibat Covid-19. Kota Tangerang Selatan berpotensi mengalami kenaikan kasus Covid-19 karena berbatasan langsung dengan DKI Jakarta yang merupakan episentrum persebaran Covid-19, sehingga peneliti tertarik untuk melakukan penelitian ini. Desain penelitian ini adalah studi analitik kasus kontrol menggunakan data sekunder dari penelusuran epidemiologi (PE) Dinas Kesehatan Kota Tangerang Selatan bulan Maret 2020-Juli 2021. Data PE diperoleh dari portal New All Record (NAR) yang memuat data pasien Covid-19 termasuk identitas, gejala, komorbid, dan status pasien yang dikumpulkan dari wawancara atau anamnesis di fasyankes. Variabel independen pada penelitian ini adalah hipertensi dan variabel dependen adalah kematian pasien Covid-19 terkonfirmasi positif. Variabel kovariat yang diteliti antara lain usia, jenis kelamin, diabetes mellitus (DM), penyakit kardiovaskular (CVD), gangguan imunologi, penyakit ginjal kronik (PGK), penyakit paru obstruktif kronik (PPOK), dan obesitas. Jumlah sampel kelompok kasus dan kontrol masing-masing sebanyak 344 sehingga total sampel adalah 688 sampel. Analisis data yang dilakukan adalah univariat, bivariat, dan multivariat. Proporsi pasien Covid-19 yang memiliki hipertensi pada kelompok kasus adalah 44.77% dan pada kelompok kontrol sebanyak 8.14%. Analisis multivariat dengan regresi logistik dihasilkan OR=9.08 (p-value=0.000; 95% CI 4.62-17.84) setelah dikontrol dengan usia, DM, PGK, interaksi hipertensi dan usia, hipertensi dan DM, dan hipertensi dan penyakit kardiovaskular. Penelitian ini memiliki bias informasi karena pengumpulan data berdasarkan anamnesis.
Faktor Gejala dan Komorbid yang Berhubungan dengan Kematian Pasien COVID-19 di Tangerang Selatan, November 2020-Mei 2021 Ade Ayu Lanniari Harahap; Helda Helda
Jurnal Epidemiologi Kesehatan Komunitas Vol 8, No 2 : Agustus 2023
Publisher : Master of Epidemiology, School of Postgraduate Studies, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v8i2.11939

Abstract

Background : Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The number of confirmed cases and deaths of COVID-19 continues to increase globally. Epidemiology and clinical characteristics of COVID-19 cases from Indonesia are scanty. High-quality evidence to understand the disease and can be used as a basis for policymaking. Therefore, this study was conducted to determine the symptom factors and comorbidities associated with mortality in COVID-19 patients in South Tangerang from November 2020 to May 2021.Methode : A Case-control study of confirmed cases of COVID-19 in South Tangerang. The cases included 337 COVID-19 patients who died and 347 controls who were still alive. Data on age, gender, symptoms, and comorbidities were collected through Epidemiological Surveillance (ES) of COVID-19 patients at the South Tangerang Health Office from November 2020 to May 2021 in association with death and analyzed using chi-square test and simple logistic regression.Result : The results of multivariate analysis showed that risk factors such as age (OR=5.059; 95% CI: 3.209-7.974), gender (OR=2.650; 95% CI: 1.758-3.996), fever symptoms (OR=0.499; 0.331- 0.753), co-morbidities with diabetes mellitus (OR=15.94; 95% CI: 7.397-34.350), hypertension (OR=4.005; 95% CI: 2.440-6.572), heart disease (OR=7.249; 95% CI: 2.893-18.162 ) and chronic kidney failure (OR=12,523, 95% CI: 1,571-99,808) had an influence on the incidence of death of COVID-19 positive patients in South Tangerang.Conclusion : These findings indicate that older age, male gender, symptoms of fever, and comorbidities include a history of diabetes mellitus, hypertension, heart disease, and kidney failure due to the death of COVID-19 patients in South Tangerang. The need to enhance specific public health measures to reduce the risk of death in patients infected with COVID-19.
Central Obesity as A Risk Factor For Prediabetes Rezavitawanti Rezavitawanti; Helda Helda
Asian Journal of Social and Humanities Vol. 2 No. 9 (2024): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v2i9.347

Abstract

Central obesity has become a health problem and is associated with the incidence of prediabetes. Prediabetes is characterized by impaired fasting blood glucose (GDPT) or impaired glucose tolerance (TGT) or both without any complaints and symptoms, and is a condition that precedes the occurrence of type 2 diabetes mellitus. This study aims to prove central obesity as a risk factor for prediabetes by calculating the prevalence ratio. The method of this research is observational analysis with a cross-sectional design approach. The respondents of the study were the community around the work area of the Jati Ranggon health center who met the inclusion and exclusion criteria, totaling 1241 people, 523 men and 718 women. The prevalence of central obesity in this study was 39.6%. The prevalence of prediabetes is 18.8%, prediabetes with central obesity is 27.9% and non-central obesity prediabetes is 12.8%. Bivariate analysis with chi-square showed a relationship between age and the incidence of prediabetes (RP=1.62, 95% CI 1.24-2.11 and p= <0.001), hypertension with the incidence of prediabetes (RP=1.58CI 95% 1.22-2.04, p=<0.001), gender with prediabetes (RP=1.47, 95% CI 1.12-1.94, and p=0.005), general obesity with prediabetes (RP=1.87, 95% CI 1.44-2.42 and p=<0.001), smoking with the incidence of prediabetes (RP= 0.54, 95% CI 0.33-0.88 and p=0.013). The results of multivariate analysis with cox regretion showed that the variables that affected prediabetes were central obesity (RP=1.87, CI95% 1.40-2.50, p=<0.001) and general obesity (RP=1.42, CI95% 1.06-1.89, p=0.017). Central obesity is a risk factor for prediabetes with a prevalence ratio of 2.18.