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All Journal Indonesian Journal of Cardiology ACI (Acta Cardiologia Indonesiana)

Harris Hasan

Department Of Cardiology And Vascular Medicine, Faculty Of Medicine, Universitas Sumatera Utara / Haji Adam Malik General Hospital, Medan, North Sumatera

Author-ID : 3375030

Health Professions Medicine & Pharmacology

Published : 9 Documents Claim Missing Document

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Significance of Mitral M-Mode Vp (Velocity Propagation) for Estimating Mitral Valve Area and Severity in Mitral Stenosis Bertha Gabriela Napitupulu; Harris Hasan
ACI (Acta Cardiologia Indonesiana) Vol 5, No 1 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Background: Confirming mitral valve area (MVA) by planimetry is one of the standard procedures for assessing mitral stenosis but MVA were frequently need to be confirmed by other echocardiography parameters that only available in sophisticated centers. Our aim was to evaluate the significance of a simple mitral inflow color M-mode velocity propagation (Vp) for estimating MVA and MS severity.Methods: The best color view of MS jet were taken from apical 4 chamber, the nyquist limit were adjusted for aliasing the central highest velocity, then M-mode were applied to MV to calculate Vp by measuring the slope of the blue jet with the first aliasing velocity. MVA,PHT and mean transmitral gradient were analyzed with Pearson correlation and linear regression. Predictive discrimination value of Vp were analyzed by ROC.Results: Thirty one MS patients had mean MVA planimetry 0.99 ± 0.35 cm2 and mean Vp 64.49 ± 21.63 cm/s. Vp that were found to have a strong negative correlation with MVA (Spearman rho -0.865, p < 0.01). Vp had a good predictive discrimination value as from AUC 0.931. Vp were found to have a moderate correlation with MVA by PHT ( Spearman rho -0.621, p <0.01). Vp more than 55 cm/s had 93.8% sensitivity and 86.7% specificity to distinguish severe MS.Conclusions: By making use of the high temporal resolution of M-mode, a simple color Mitral M-Mode Vp were found statistically significant for estimating MVA severity in MS. Interventional decision for MS could also consider Vp for its strong correlation with MVA on MS, especially for helping on targeting moderate to severe MS in rural and limited centers.

Significance of Electrocardiographic QTc Interval on Assessment of Left Ventricular Diastolic Dysfunction in Hypertensive Patient: A Simple Screening Tool Sheila Dhiene Putri; Harris Hasan; Refli Hasan; A. Afif Siregar; Nizam Akbar; Cut Aryfa Andra
ACI (Acta Cardiologia Indonesiana) Vol 5, No 1 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Background: Diastolic dysfunction as part of heart failure with preserved ejection fraction (HFpEF) has gain interests, due to the increasing prevalence rate and poor prognosis. Besides the mechanism is not fully understood, there are some difficulties in detecting the presence of diastolic dysfunction. Previous studies have shown correlation between some electrocardiographic parameters and diastolic function. Furthermore, the aim of this study is to assess the diagnostic value of the QTc interval in detecting left ventricular diastolic dysfunction.Methods: A cross sectional study was conducted on patients with clinical suspicion of heart failure. Electrocardiographic examination was performed to obtain QTc interval (msec) using the Bazett formula. Left ventricular diastolic function was assessed using Tissue Doppler Imaging by echocardiography. Using correlation test and ROC method, the relationships between QTc interval and LV diastolic function were investigated.Results: Of 82 patients analyzed, there were 62 patients (75.9%) known to have diastolic dysfunction. The QTc interval was found to be longer in the group with diastolic dysfunction compared to the normal group (442.9±27 vs. 402.1±18.2, p <0.001). There was a strong negative correlation between the QTc interval and diastolic function (r = -0.619; p <0.001). Using ROC analysis, the cut off point for QTc interval was 410 ms with 91% sensitivity, 70% specificity, and 90% positive predictive value.Conclusion: The QTc interval is an accurate, simple and highly feasible electrocardiographic parameter as a screening tool to determine the presence of left ventricular diastolic dysfunction.

Comparison of TIMI Flow in STEMI Patients With and Without Resolution on Reciprocal ST Segment Depression Obtaining Fibrinolytic Alteplase Therapy Aldino Satria Adhitya; Harris Hasan; Refli Hasan; A. Afif Siregar; Zulfikri Mukhtar; Ali Nafiah Nasution
ACI (Acta Cardiologia Indonesiana) Vol 5, No 2 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Background: STEMI patients need revascularization to improve blood flow and myocardial reperfusion. Further information can be obtained from the ECG including infarct size and prognosis of STEMI patients. ST segment depression (STSD) in reciprocal leads isassociated with poorer prognosis. STEMI patients with STSD resolution have a better TIMI flow compared with no STSD resolution. The aim of this study was to look for TIMI flow for STEMI subjects who received fibrinolytic therapy with and without resolution of STSD shortly after fibrinolytic.Methods: This study is a prospective cohort study, in which 60 STEMI subjects, patients performed coronary angiography diagnostics to assess TIMI flow. The resolution on reciprocal STSD is defined as a decrease of 50% in the amount of reciprocal STSD in 90- minute after fibrinolytic therapy started.Results: Bivariate analysis showed that ejection fraction <40% with p = <0.001; QRS duration, p = <0.001; anterior STEMI with p = <0.001; are significant factors for STSD resolution. QRS Fragmentation with p = <0.001; STSD resolution with p = <0.001; ST elevation resolution with p = <0.001; are significant factors for TIMI Flow. In the TIMI Flow comparison with reciprocal STSD resolution; the resolution of reciprocal STSD has a better TIMI flow with OR 28 [(5.5-141.9), p = <0.001].Conclusion: There were differences in TIMI Flow in STEMI patients with reciprocal STSD resolution and without reciprocal STSD resolution who received fibrinolytic alteplase therapy, where STEMI patients with reciprocal STSD resolution had a better TIMI Flow compared with STEMI patients without reciprocal STSD resolution.

Co-Authors A. Afif Siregar A. Afif Siregar Abdul Halim R Abdullah Afif Siregar Abdullah Afif Siregar Aldino Satria Adhitya Ali Nafiah Nasution Ali Nafiah Nasution Ali Nafiah Nst Andika Sitepu Andra, Cut Aryfa Andre Pasha Ketaren Andre Pasha Ketaren Anggia Chairuddin Lubis Bertha Gabriela Napitupulu Hilfan Ade Putra Lubis Jaya Suganti Jaya Suganti Komaria Komaria Mustika Fadhilah Sarahazti Nizam Akbar Nizam Zikri Akbar Refli Hasan Refli Hasan Sheila Dhiene Putri Zainal Safri Zulfikri Mukhtar Zunaidi Syahputra Zunaidi Syahputra

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Journal : ACI (Acta Cardiologia Indonesiana)