Article Per Year (5 Year)
p-Index From 2019 - 2024
0.444
P-Index
This Author published in this journals
All Journal Buletin Farmatera ACI (Acta Cardiologia Indonesiana)
Sheila Dhiene Putri
Department Of Cardiology, Faculty Of Medicine, Universitas Muhammadiyah Sumatera Utara
Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Significance of Electrocardiographic QTc Interval on Assessment of Left Ventricular Diastolic Dysfunction in Hypertensive Patient: A Simple Screening Tool Sheila Dhiene Putri; Harris Hasan; Refli Hasan; A. Afif Siregar; Nizam Akbar; Cut Aryfa Andra
ACI (Acta Cardiologia Indonesiana) Vol 5, No 1 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (694.18 KB) | DOI: 10.22146/aci.44551

Abstract

Background: Diastolic dysfunction as part of heart failure with preserved ejection fraction (HFpEF) has gain interests, due to the increasing prevalence rate and poor prognosis. Besides the mechanism is not fully understood, there are some difficulties in detecting the presence of diastolic dysfunction. Previous studies have shown correlation between some electrocardiographic parameters and diastolic function. Furthermore, the aim of this study is to assess the diagnostic value of the QTc interval in detecting left ventricular diastolic dysfunction.Methods: A cross sectional study was conducted on patients with clinical suspicion of heart failure. Electrocardiographic examination was performed to obtain QTc interval (msec) using the Bazett formula. Left ventricular diastolic function was assessed using Tissue Doppler Imaging by echocardiography. Using correlation test and ROC method, the relationships between QTc interval and LV diastolic function were investigated.Results: Of 82 patients analyzed, there were 62 patients (75.9%) known to have diastolic dysfunction. The QTc interval was found to be longer in the group with diastolic dysfunction compared to the normal group (442.9±27 vs. 402.1±18.2, p <0.001). There was a strong negative correlation between the QTc interval and diastolic function (r = -0.619; p <0.001). Using ROC analysis, the cut off point for QTc interval was 410 ms with 91% sensitivity, 70% specificity, and 90% positive predictive value.Conclusion: The QTc interval is an accurate, simple and highly feasible electrocardiographic parameter as a screening tool to determine the presence of left ventricular diastolic dysfunction.
Statins' Protective Effect For The Prevention Of Atrial Fibrillation Incidence After Coronary Artery Bypass Surgery Sheila Dhiene Putri; Zainal Safri
Buletin Farmatera Vol 7, No 2 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i2.9736

Abstract

Abstract: Atrial fibrillation (AF) after cardiac surgery is associated with an increased risk of complications, length of stay, and cost of care. Recent studies have demonstrated that statins have pleiotropic effects, including anti-inflammatory effects and preventing atrial fibrillation (AF). The objective of this study was to assess the efficacy of preoperative statin therapy in preventing AF after coronary artery bypass grafting (CABG). 53 patients underwent CABG in our hospital from February to August 2018. Patients were randomized into two groups to examine the effect of statins: those with atorvastatin 20 mg/day during the preoperative period (Atorvastatin group, n = 26) and those with rosuvastatin 10 mg/day (Rosuvastatin group, n = 27). The primary end-point is postoperative AF (POAF), with an overall incidence of postoperative AF of 11.3%. Postoperative AF incidence was insignificantly different between the atorvastatin and rosuvastatin groups (7.7% vs. 14.8%; p = 0,669). Our study indicated that atorvastatin had a similar protective effect to rosuvastatin in terms of post-operative AF prevention.Keywords: statin, post-operative AF
Co-Authors A. Afif Siregar Andra, Cut Aryfa Harris Hasan Nizam Akbar Refli Hasan Zainal Safri