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All Journal Jurnal Kedokteran dan Kesehatan Herb-Medicine Journal
Paramita Septianawati
Universitas Muhamadiyah Purwokerto
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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PENGARUH EKSTRAK ETANOL DAUN KEMANGI (Ocimum bacilicum L.) TERHADAP KADAR β2 MIKROGLOBULIN, ASAM URAT DAN GAMBARAN HISTOLOGI GINJAL PADA TIKUS PUTIH GALUR WISTAR (Rattus novergicus strain Wistar) YANG DIINDUKSI MONOSODIUM GLUTAMAT Paramita Septianawati; Hernayanti Hernayanti; Gratiana Ekaningsih W
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 3, No 1 (2020): Herb-Medicine Journal April 2020
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v3i1.6638

Abstract

AbstractBasil leaves (Ocimum basilicum) is one of the traditional medicinal plants that is used as medicine.This study aims to determine the effect of giving basil leaves on levels of Beta 2 microglobulin, uric acid and kidney histology in white wistar-induced rats in MSG and determine the effective dose of basil leaves in an effort to improve kidney function.This study used 25 male Wistar strain rats with body weight 200-230 g. The test animal group was divided into five groups based on the stage of treatment. The first treatment group was a control group consisting of five mice that were not given basil leaf extract or MSG, the second treatment group was the group that was only given MSG without being given basil leaf extract, the third treatment group was the group given MSG followed by basil leaf extract dose 87, 5 mg / kgBB, the fourth treatment group was the group that was given MSG followed by the administration of basil leaf extract with a dose of 175 mg / kgBW, and the fifth treatment group was the group that was given MSG followed by the administration of basil leaf extract at a dose of 350 mg / kgBB. At the end of the treatment, rats were drawn for blood analysis of B2M levels and uric acid levels and kidney tissue uptake, as well as analyzing kidney tissue histology.The results showed that there were differences between Beta 2 microglobulin, uric acid and kidney histopathology of rats receiving basil leaf extract compared with MSG group without basil leaf extract. This study concludes that consuming basil leaf extract can reduce levels of B2M and uric acid and improve kidney histology induced by MSG.
Perbandingan Pengetahuan Dasar Tentang Kriteria Seleksi Donor Darah Pada Mahasiswa Kedokteran Negeri dan Swasta di Purwokerto Tahun Pertama Paramita Septianawati; Dharma Koosgiarto; Tisna Sendy Pratama; Andi Muh. Maulana; Abdul Hakim Nitiprodjo; Titik Kusumawinakyu
Jurnal Kedokteran dan Kesehatan Vol 19, No 1 (2023): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jkk.19.1.98-104

Abstract

Transfusi darah merupakan tindakan yang dapat menyelamatkan nyawa ribuan orang di seluruh dunia karena darah merupakan elemen penting dalam kehidupan manusia. Kajian tentang pengetahuan mengenai kriteria donor darah dapat bermanfaat dalam keberhasilan pelaksanaan program donor darah. Tujuan penelitian adalah untuk mengetahui tingkat pengetahuan dasar tentang kriteria seleksi donor darah pada mahasiswa kedokteran tahun pertama di Purwokerto. Sampel penelitian ini yaitu 144 mahasiswa fakultas kedokteran di universitas negeri dan universitas swasta di Purwokerto. Analisis statistik dilakukan dengan menggunakan software SPSS. Pada 144 mahasiswa terdiri dari 72 mahasiswa FK negeri dan 72 mahasiswa FK swasta yang terlibat dalam penelitian ini. Hasil analisis didapatkan perbedaan pada kriteria seleksi donor darah mengenai penyakit kulit pada vena yang akan ditusuk (p=0,049) dan tidak ditemukan perbedaan antara dua universitas mengenai kriteria seleksi donor darah. Mayoritas mahasiswa sudah mengetahui kriteria seleksi donor darah yang baik yang dapat menjadi penyumbang darah atau pendonor. Perlu meningkatkan pengetahuan mahasiswa fakultas kedokteran baik di negeri maupun swasta dengan menggunakan media informasi dan komunikasi yang efektif-efisien khususnya materi transfusi darah.
Co-Authors Abdul Hakim Nitiprodjo Andi Muh. Maulana Dharma Koosgiarto Gratiana Ekaningsih W HERNAYANTI HERNAYANTI Tisna Sendy Pratama Titik Kusumawinakyu