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Johan Christian Silaen
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Gambaran Profil Hematologi Dalam 24 Jam Pertama Pada Pasien Sepsis Di Unit Neonatus RSUD Dr. Pirngadi Medan Tahun 2017-2018 Alpa Exaudi Siahaan; Johan Christian Silaen; Leo Simanjuntak
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (222.255 KB) | DOI: 10.36655/njm.v6i2.243

Abstract

Background: Neonatal sepsis is a clinical syndrome on infants aged 28 days or more. According to WHO data on 19th April 2018, estimated 3 million newborns and 1.2 million children suffer from sepsis globally every year. Hematological profile assessment can be used as a clinical guide to diagnose sepsis and early management of patients with early onset, especially in hospitals with limited facilities and the examination data can be obtained faster. Objective: This study was aimed to determine the hematological profile in sepsis patients in neonatal unit at RSUD Dr. Pirngadi Medan. Method: This research was a descriptive cross-sectional design. The research sample was selected by total sampling. Results: The results of the study were found from 74 neonates, 44 (59.5%) were male. Neonates with normal labor were 57 (78.1%) and survived 45 (60.8%). It was found that leukocytes (76.4%), neutrophils (60%), monocytes (87.9%), and hemoglobin (40.3%) were increased. Conclusion: The hematological profile can be used as a clinical assessment of sepsis at the first 24 hours on neonates. Hematological examination found an increased leukocytes, neutrophils, monocytes, and hemoglobin in neonatal sepsis patients at the first 24 hours.
Perbandingan antara Rasio Neutrofil Limfosit dan Trombosit pada Kebocoran Plasma Anak Fransisco Aditia Sembiring Meliala; Johan Christian Silaen; Novita Hasiani Simanjuntak
Nommensen Journal of Medicine Vol 7 No 1 (2021): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (42.389 KB) | DOI: 10.36655/njm.v7i1.264

Abstract

Background: Dengue virus infection is a global health problem. Dengue Hemorrhagic Fever (DHF) has become a global attention because of children death due to plasma leakage. Plasma leakage is a symptom of critical phase in children that occurs on the 3rd to 5th day. Neutrophil lymphocyte (NL) ratio and platelet count change can be seen in critical phase of plasma leakage which can help process of patient’s therapy. Objective: This study aimed to compare the NL ratio and platelets count on plasma leakage in children with DHF. Methods: This study was an analytical study with cross-sectional design. The sample was children with DHF at RSUD Dr.Pirngadi Medan. The data of this study were analyzed by computer software, used an unpaired t test with p <0.05. Results: This study found that the most age of DHF was 6-10 years old, most gender are male and DHF grade 1. Unpaired t test found the average difference between NL ratio and platelet with value of p = 0.043 (p<0.05). Conclusion: Plasma leakage average on NL ratio is higher than plasma leakage average on platelets that occurs in children with DHF at RSUD Dr.Pirngadi Medan.
Co-Authors Alpa Exaudi Siahaan Fransisco Aditia Sembiring Meliala Leo Jumadi Simanjuntak Simanjuntak, Novita Hasiani