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Anggun Mahirotun Nur Sholikhah
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Darussalam Gontor
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Formulasi Tablet Effervescent Daun Kersen (Muntingia calabura L.) dengan Variasi KonsentrasiEffervescent Mix Anggun Mahirotun Nur Sholikhah; Surya Amal; Fitria Susilowati
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.923 KB) | DOI: 10.21111/pharmasipha.v2i2.2779

Abstract

Muntingia calabura L. is one of the type genus Muntingia which grows ever green and always has a lot of benefits but has not been used optimally. This study aims to utilize Muntingia calabura leaves take one form of pharmaceutical preparations namely effervescent tablet. Effervescent tablets are made using dry granulation of the metanol : water extract Muntingia calabura leaves. This study used variations of the concentration of effervescent mix to know the best concentration of the effervescent mix. Method to make it in relative humidity condition (RH) and appropriate temperature. Three of the formula that has made qualified evaluation of granules (time flow, angle of repose, and compresibility) and evaluation of effervescent tablets (weight variation, hardness test, time dissolved, assay test water, and pH level test). The results of analysis, showed that the three all formulas meet the requirement of test characteristics of granule and effervescent tablet. Based on the results of the research can be conclude that the formula with a concentration of 60% (formulation 2) effervescent mix is the best formula. This is due to the formula for concentration of 60% effervescent mix is the concentration that is ideal concentration for effervescent tablets.
Co-Authors Fitria Susilowati Surya Amal