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Isabella Riandani
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Health Professions Medicine & Pharmacology

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Association between immunization coverage and atopy in children with or without family history of atopic disease Isabella Riandani; Budi Setiabudiawan; Cissy B. Kartasasmita
Paediatrica Indonesiana Vol 48 No 6 (2008): November 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.654 KB) | DOI: 10.14238/pi48.6.2008.358-63

Abstract

Background Atopic diseases are determined by the interactionbetween genetic and environmental factors. The possible effectsof immunization, as one of environmental factors, on atopy remaina matter of controversy.Objective We conducted an observational clinical epidemiologyto find out the protective effect of high vaccination coverage toatopy in children.Methods During January through March 2006, 150 of749 childrenat Garuda, Padasuka, and Babakan Sari Primary Health Care inBandung were randomized from group with and without familyhistory of atopic disease. Atopy derived from skin prick test andtotal serum lgE was evaluated. Atopy was defined as a positiveskin test to any of the eight allergens tested. The immunizationswere recorded from Kartu Menuju Sehat (KMS). Statistical analysesincluded Chi square to compare prevalence, independent T-testand Mann-Whitney to compare mean.Results Atopy was found in 28.2% of284 subjects, of which 32.4%with and 23.9% without a family history of atopic disease. Themedian of total serum lgE level was higher in children with familyhistory of atopic disease and in atopy children. Children weregrouped according to total dose of basic immunizations (0-17 and2: 18) based on Program Pengembangan Imunisasi (PPI). There wasnonsignificant association between total doses of immunizationand atopy. Even though no statistically significant, the cumulativeimmunization doses were inversely related to the median of totalserum IgE level.Conclusions The immunization coverage has not decreased atopyrisk.
Tourette’s syndrome Meita Dhamayanti; Isabella Riandani; Lelly Resna
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.946 KB) | DOI: 10.14238/pi44.1.2004.37-40

Abstract

The aim of this report was to show that mostbehavioral disorders need multidisciplinary manage-ment by behaviorist, neurologist, psychiatrist, psy-chologist and pedagogue, and to give more informa-tion about Tourette’s syndrome so that it can be de-tected earlier. Therefore, children who suffer from itcan live a better life and develop their ability.
Co-Authors BUDI SETIABUDIAWAN Cissy B. Kartasasmita Lelly Resna Nugrahawati Meita Dhamayanti