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Sri Rezeki S Hadinegoro
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Lactose malabsorption based on breath hydrogen test in children with recurrent abdominal pain Elizabeth Yohmi; Aswitha D Boediarso; Sri Rezeki S Hadinegoro
Paediatrica Indonesiana Vol 44 No 6 (2004): November 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (831.356 KB) | DOI: 10.14238/pi44.6.2004.215-21

Abstract

Background Recurrent abdominal pain (RAP) is common amongschool-age children. Previous studies found that lactose malab-sorption has an important role in RAP in children. Up to date, dataon the prevalence of lactose malabsorption in children with RAPin Indonesia has not been available.Objective To elicit the prevalence of RAP and lactose malabsorption inchildren with RAP, and to determine associated foods that cause RAPin children with and without lactose malabsorption, the frequency oflactose intolerance during breath hydrogen test (BHT), and also theonset and duration of the symptoms after a lactose load.Methods This was a cross-sectional study conducted on juniorhigh school students who suffered from recurrent abdominal pain.Results Of 1054 students screened, 157 (14.9%) fulfilled the Apley’scriteria for RAP. Of 157, 85 children were enrolled and underwentBHT. Fifty five of them (65%) were girls. Lactose malabsorptionwas found in 68 (80%) subjects. Milk and yogurt were the mostfrequent products that cause symptoms of RAP in our subjectswho mostly (80%) were malabsorber. Lactose intolerance duringBHT was found in 69 (81%) children. Symptoms appeared in 30minutes after lactose ingestion, and the most frequent symptomwas abdominal pain (44%). Lactose intolerance symptoms disap-peared in about 15 hours.Conclusions The prevalence of RAP in children aged 12-14 yearswas 14.9%. The prevalence of lactose malabsorption in childrenwith RAP was 80%. Milk and yogurt were the most frequent productsthat cause symptoms of RAP in our subjects who mostly weremalabsorbers. The frequency of lactose intolerance during BHTwas 81%, and the symptoms lasted within approximately 15 hours
Profiles of patients with urinary incontinence in the Department of Child Health, Cipto Mangunkusumo Hospital Eveline P N; Taralan Tambunan; Sri Rezeki S Hadinegoro
Paediatrica Indonesiana Vol 45 No 2 (2005): March 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.2.2005.87-92

Abstract

Background Urinary incontinence (UI) in children is a form ofwetting. Early diagnosis and treatment are mandatory to avoidcomplications such as recurrent urinary tract infections (UTI),vesicoureteral reflux (VUR), or renal damage.Objective To study the profiles and clinical course of UI in chil-dren treated in Cipto Mangunkusumo Hospital.Methods The study was divided into 2 parts. The first part was areview of patients with UI at Cipto Mangunkusumo Hospital fromJanuary 2000 to December 2003. The second was a case seriesof patients followed up for at least 6 months.Results There were 35 UI patients aged 3 months to 16 years,mostly between 1 to 5 years old, 16 were males and 19 females.The most prevalent etiology was myelodysplasia (15 cases) fol-lowed by posterior urethral valve, and bladder tumor. The mostprominent clinical presentation of neurophatic bladder-sphincterdysfunction was wetting, while those of patients with structural in-continence and non-neuropathic bladder-sphincter dysfunctionwere fever and polakysuria. Most patients had been suffering fromrenal insufficiency since their first visit. Clean intermittent catheter-ization (CIC) was the treatment of choice. In a six-month follow-upof 14 patients who received adequate treatment, renal functioncould be maintained at relatively stable condition in most cases.Conclusions Myelodysplasia was the most common etiology ofUI. Most patients had renal insufficiency or renal failure since theirfirst visit, reflecting a extended period of relapse before patientsseek medical help. Renal function can be maintained by adequatetreatment in most cases
Lactose malabsorption in junior high school children Aswitha D. Budiarso; Deny Sofia; Sri Rezeki S Hadinegoro; Badriul Hegar
Paediatrica Indonesiana Vol 43 No 2 (2003): March 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi43.2.2003.46-50

Abstract

Background The prevalence of lactose malabsorption varieswidely throughout the world. Only people of Caucasian geneticbackground continue to produce high amount of lactase throughoutadulthood. Previous studies in Indonesia revealed that theprevalence of lactose malabsorption was 21-58% in children aged3-11 years.Objective To determine the prevalence of lactose malabsorptionin the older age group and whether a change in milk drinking habitcan affect it.Methods A cross sectional descriptive study was conducted on98 children aged between 12 and 14 years (junior high school) inJakarta. Lactose malabsorption was evaluated with LactometerBreath Hydrogen Test (Hoek Loes, Amsterdam). Milk drinking habitwas recorded, and drinking at least 1 glass of milk everyday since6 months or more before the study was considered as regular milkdrinking.Results This study showed 73% of the children had lactose malabsorption.Regular milk drinking habit was found in 32 (33%) childrenand lactose malabsorption occurred in 26. From 66 childrenwho were irregular milk drinkers, lactose malabsorption was foundin 46 (70%). Lactose intolerance was about the same in both groups.Conclusion There was an increasing prevalence of lactose malabsorptionin older children. Milk drinking habit is a major concernto review the practical implications of lactose malabsorption.
Co-Authors Aswitha D Boediarso Aswitha D. Budiarso Badriul Hegar Deny Sofia Elizabeth Yohmi Eveline P N Taralan Tambunan