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Harsoyo N.
Department of Child Health, Universitas Diponegoro Medical School/Dr. Kariadi Hospital, Semarang, Central Java
Health Professions Medicine & Pharmacology

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Use of acetyl cysteine in respiratory tract disease in children Moeljono S. Trastotenojo; Harsoyo N.; Anggoro D. B. Sachro; Said H. W.; A. G. Soemantri
Paediatrica Indonesiana Vol 24 No 1-2 (1984): January - February 1984
Publisher : Indonesian Pediatric Society

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Abstract

In this study 54 children with respiratory tract disease: bronchopneumonia, bronchial asthma, bronchiolitis and tuberculosis all treated with acetylcysteine and placebo were analysed. In thirty eight patients with bronchopneumonia 20 were treated with acetylcysteine and 16 with placebo; in 9 patients with bronchial asthma 5 were treated with acetylcysteine and 4 with placebo. Of the 5 patients with bronchiolitis, 3 were treated with acetylcysteine and the remainder with placebo. Two children with tuberculosis were given acetylcysteine. The analysis of patients suffering from bronchopneumonia showed no statistically significant difference between acetylcysteine and placebo. Patients with bronchial asthma also showed no significant difference between both groups. There is a statistically significant difference between the results on the first, third, fifth and seventh day of treatment of the group of patients treated with acetylcysteine. No attempts were made to analyse bronchiolitis and tuberculosis. No side effects were seen in this study.
Intrathecal Hydrocortisone in the Treatment of Tuberculous Meningitis (Preliminary Report) Harsoyo N.; Moeljono S. Trastotenojo; Soejono Soejono; Dedy Abubakar; Indra Warman
Paediatrica Indonesiana Vol 16 No 9-10 (1976): September - October 1976
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (619.827 KB) | DOI: 10.14238/pi16.9-10.1976.355-60

Abstract

A trial on the treatment of tuberculous meningitis with intrathecal hydrocortisone, beside INH, PAS, and Streptomycin, performed at the Dr. Kariadi General Hospital in October 1972, is reported. Eighteen patients were treated, giving good results; 5.6% mortality were noted. A great number of complications of optic nerve atrophy (61.1 %) were found and 22.2% with early atrophy recovered. The results are better compared with those of Choremis et al. (1957) who found a mortality of 13.7% among 29 patients with tuberculous meningitis treated in the same way, except P.A.S.
Treatment of Bronchopneumonia with Spiramycine (Rovamycine) Soejono Soejono; Moeljono S. Trastotenojo; Harsoyo N.
Paediatrica Indonesiana Vol 16 No 9-10 (1976): September - October 1976
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.005 KB) | DOI: 10.14238/pi16.9-10.1976.396-402

Abstract

Fifty-seven children with bronchopneumonia, comprising 32 male and 25 female, were admitted to the Department of Child Health, Dr. Kariadi Hospital, Semarang, during the period of May 1972 - May 1973. Varying in ages between 16 days and 7 years, 36 of them were less than one year old. They were treated with spiramycine (Rovamycine) given orally in a dosage of 50 mg/kg body weight daily in three divided doses. The failure was 9 out of 57 cases (15.8%) and in infants 7 out of 36 cases (19.4%). The culture of infants revealed 36.1% staphylococcus and in older children showed 4.8%. All cases of staphylococcus as a single cause which was treated with spiramycine gave good results. No side effects of spiramycine were noted. The study showed that spiramycine has a value in the treatment of childhood bronchopneumonia especially in staphylococcal injections in infants.
Co-Authors A. G. Soemantri Anggoro D. B. Sachro Dedy Abubakar Indra Warman Moeljono S. Trastotenojo Said H. W. Soejono Soejono