Jimmy Passat
Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta

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Diagnosis and Management of Brain Tumors in Children Taslim S. Soetomenggolo; Hardiono Pusponegoro; Jimmy Passat; Dwi Putro Widodo; Sofyan Ismael
Paediatrica Indonesiana Vol 35 No 7-8 (1995): July - August 1995
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi35.7-8.1995.185-9

Abstract

Brain tumors are the second most common malignancy and the most common solid tumors found in childhood. During 11 months 19 patients with brain tumors were hospitalized at the Department of Child Health, Dr. Cipto Mangunkusurno Hospital, Jakarta, 10 of them were males. The youngest patient was 5 months old and the oldest was 13 years old. The important signs and symptoms in establishing diagnosis were the non-localizing signs and symptoms, i.e., nausea and vomiting. The most frequent localizing signs and symptoms were papilledema, cranial nerves palsy, ataxia and incoordination, hemiparesis, visual disturbances, and optic atrophy. Focal seizures were rare. Most of the tumors were in infratentorial region, and metastatic tumors were rare. The mortality of this series was high due to the severity of the disease. The most frequent of tumors are astrocytomas and medulloblastomas.
Blood Gas Analysis in Neonatal Tetanus Taslim S. Soetomenggolo; Dwi Putro Widodo; Jimmy Passat; Sofyan Ismael
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January - February 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.487 KB) | DOI: 10.14238/pi34.1-2.1994.44-7

Abstract

We reviewed the results of arterial blood gas analysis in 127 patients with neonatal tetanus on admission, and in 52 of such patients on the day before they died. All patients were hospitalized at the Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta. On admission, most patients showed uncompensated metabolic acidosis. The mortality of patients wjth pH ofless than 7 was 100%. There was no significant difference between the mortality of patients with pH 7.35-7.45 and those with pH of less than 7.35. Analysis of acid-base balance indicated that ventilatory fw1ure was the most common finding in 52 patients who subsequently died. We recommend using intravenous fluid containing a combination of 5% dextrose and sodium bicarbonate with 4 : 1 (vol/vol) ratio from the fust day of hospitalization to reduce the possibility of the development of ongoing metabolic acidosis in patients with neonatal tetanus. Maintaining adequate ventilation is mandatory ln such patients.
Evaluation of Mortality of Patients with Neonatal Tetanus Taslim S. Soetomenggolo; Hardiono D. Pusponegoro; Jimmy Passat; Sofyan Ismael
Paediatrica Indonesiana Vol 34 No 5-6 (1994): May - June 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (493.291 KB) | DOI: 10.14238/pi34.5-6.1994.136-40

Abstract

During 8 years, 405 patients of neonatal tetanus were hospitalized in the Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta. Diagnosis of neonatal tetanus was based on clinical signs and symptoms. Of the 405 patients, 56.3% were males and 43.7 %. were females. Two hundreds and sixty nine (66.3 %) patients were delivered by traditional birth attendants, and only 33.6% were delivered by midwives or physicians. The overall mortality was 54.4%, with the corrected mortality of 46.7%. Severity of the disease, short incubation period, short period of onset, and the accompanying diseases were responsible for the high mortality of patients with neonatal tetanus.
Subacute Sclerosing Panencephalltis: Clinical and Laboratory Manifestations Hardiono D. Pusponegoro; Jimmy Passat; M. Hardjono Abdoerachman
Paediatrica Indonesiana Vol 32 No 5-6 (1992): May - June 1992
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (790.836 KB) | DOI: 10.14238/pi32.5-6.1992.107-17

Abstract

We reviewed clinical and laboratory findings of 12 cases of Subacute sclerosing panencephalitis (SSPE) hospitalized at our department from 1985 to 1991. All cases were diagnosed and hospitalized at the 2nd stage. The principal clinical manifestations were mental changes, myoclonus, and frequent falls. Other clinical manifestations were ocular changes, involuntary movements, loss of social contact, and spasticity. Diagnosis was based on suppression-burst pattern in EEG and positive antibody titer to measles in serum and cerebrospinal fluid. CT scan was not diagnotic, since it was either normal or showed only non-specific cortical atrophy. Eleven patients (91, 7%) recalled a history of measles in the past. Age of onset of SSPE varied among cases and was difficult to specify precisely due to its subtle nature. None of the cases had been vaccinated against measles. SSPE is a rare disease, but is almost always fatal with prolonged suffering of the patient. Based on our experience with SSPE patients, we recommend to broaden the immunization programme against measles.
Diagnosis and Management of Brain Abscesses in Children Taslim S. Soetomenggolo; Jimmy Passat; Hardiono D. Pusponegoro; Sofyan Ismael
Paediatrica Indonesiana Vol 32 No 5-6 (1992): May - June 1992
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (448.124 KB) | DOI: 10.14238/pi32.5-6.1992.118-24

Abstract

During 4 years, 20 patients with brain abscesses were hospitalized in the Departement of Child Health, Dr. Cipto Mangunkusumo General Hospital, jakarta. Of those 20 patients 11 were males and 9 were females. The youngest patient was 2 months old and the oldest was 12 years old. The important signs and symptoms in making diagnosis were the sign of injection, increased intracranial pressure, and focal neurological disorders. Laboratory examinations were of little value in establishing the diagnosls of brain abscess. By performing head CT Scan the diagnosis of brain abscess will be confirmed accurately. Of the 20 patients, 15 (75 %) suffered from single abscess and 5 (25 %) suffered from multiple abscesses. The results of treatment by surgical intervention were better than nonsurgical treatment. The high mortallty of the nonsurgical patients was caused by the severity of the disease due to the ignorancy of their parent.
Myotonia Congenita (Thomsen's Disease) Report of Five Cases in a Family Hardiono D. Pusponegoro; Jahja Zacharia; Jimmy Passat
Paediatrica Indonesiana Vol 31 No 5-6 (1991): May - June 1991
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (509.639 KB) | DOI: 10.14238/pi31.5-6.1991.170-8

Abstract

This report describes 5 out of 8 siblings who were the first cases of myotonia congenital diagnosed in our department. The parents were first cousins. Neither the parents, nor the other family members have myotonia. The affected siblings 4 boys and 1 girl, all showed a very typical myotonia especially after prolonged rest, and it could be worked off with, continuing activity. They had a muscular looking body or a herculean proportion. The diagnosis were based upon family history, clinical findings of percussion myotonia, had grip myotonia, prominent muscular hypertrophy and confirmed by electromyographic examination revealing myotonic discharges. Since there were some junctional impairments, these patients were treated with diphenylhydantoin and then with quinine sulphate, with good results. The patients related parents were much likely to be heterozygous for the same harmful recessive genes, because they had common ancestor. The role of marriage counseling is important in this kind of inherited disease, to prevent the occurrence of this inherited disorder in the next generations.