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Evi Setiadi
Department of Biochemistry, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Health Professions Medicine & Pharmacology

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HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers Adnan S. Wiharta; Evi Setiadi; H. M. Sjaifullah Noer; Triyatmo Rachimhadhi; Asri Rasad
Paediatrica Indonesiana Vol 34 No 5-6 (1994): May - June 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.132 KB) | DOI: 10.14238/pi34.5-6.1994.125-8

Abstract

Vertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulation due to failure of placental tissue function. In Cipto Mangunkusumo Hospital, Jakarta, 98 (6.4%) of 1536 pregnant mothers obseiVed during 3 years (1987 -1990) showed positive HBsAg. Six (8.3%) of 60 babies of born to HBsAg positive mothers showed positive HBsAg in their cord blood, but this disappeared after one month. All babies born to HBsAg positive mothers were vaccinated on months 0, 1, 2, and 12. HBsAg in cord blood might not play an important role in vertical transmission.
Co-Authors Adnan S. Wiharta Asri Rasad Mohammad Sjaifullah Noer Triyatmo Rachimhadhi