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Zairul Arifin
Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
Health Professions Medicine & Pharmacology

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Acute Non Lymphoblastic Leukemia in the Department of Child Health School of Medicine, University of North Sumatera/ Dr. Pirngadi Hospital Medan (1983-1988): A Preliminary Study Feraluna Nasution; Zairul Arifin; Adi Sutjipto
Paediatrica Indonesiana Vol 31 No 9-10 (1991): September - October 1991
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.091 KB) | DOI: 10.14238/pi31.9-10.1991.268-72

Abstract

A retrospective study on Acute Non Lymphoblastic Leukemia (ANLL) was conducted at the Sub Division of Pediatric Hematology, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital Medan, in a period of 5 years (1983-1988). There were 18 cases consisted of 14 (77. 78%) males and 4 (22 .22%) females with the age group of 0-2 years: 6 (30%), 2-8 years: 9 (50%), 8-15 years: 3 (30%). By the FAB classification, they were of FAB M-1: 1 (5.55%), FAB M-2: 1 (5.55%), FAB M-3: 1 (5.55%), FAB M-4: 2 (11.12%) and FAB M-6: 13 (72.23%). Only 7 (38.88%) were treated with cytostatics while the others received only supportive therapy. The result of cytostatic treatment was unsatisfactory: 4 (57.14%) died within the first 2 months of treatment, 3 (42.86%) discontinued their cytostatics treatment.
Acute Lymphoblastic Leukemia in the Department of Child Health, School of Medicine, University of North Sumatera/ Dr. Pirngadi Hospital Medan (1980 - 1988) Zairul Arifin; Feraluna Nasution; Adi Sutjipto
Paediatrica Indonesiana Vol 31 No 7-8 (1991): July - August 1991
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.182 KB)

Abstract

A retrospective study on acute lymphoblastic leukemia (ALL) was conducted to assess the pattern of childhood ALL at the Subdivision of Pediatric of Hematology, School of Medicine, University of North Sumatera/ Dr. Pirngadl Hospital, Medan, in a period of 8 years (1980 - 1988). There were 120 cases, consisting of 63 (51.5%) males and 57 (47.5%) females. By the FAB classification (Bennett, 1976; 77.5% ) were found as FAB L1, 25 (20.8%) as FAB L1, and 2 (1.7%) as FAB L 3. The youngest was 4 months old. The majority of signs and symptoms appeared In the forms of pallor 102 (85%), fever 84 (70%), hemorrhage 52 (43.3%), hepatomegaly 64 (53.3%), splenomegaly 54 (45%) and lymphadenopathy 18 (15%). On first admission, 76 (63.33%) cases were with a leukocyte count of less than 20,000/ ul, and 72 (60%) with Hb content of less than 5 g/dl. Twenty one cases died In the first year. The received cytostatic protocol; 11 (S2.38'1o) were treated regularly and first remission were found in 8 (72. 73%) cases. The average of admissions per year for the age group of 2·8 years was higher than the age groups of 0·2 years and 8-16 years (p < 0.05).
Co-Authors Adi Sutjipto Feraluna Nasution