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All Journal Paediatrica Indonesiana
Yudha Fadhol Arafah
Gadjah Mada University
Health Professions Medicine & Pharmacology

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Methylprednisolone as an alternative therapy for Kawasaki disease: case series Yudha Fadhol Arafah; Sasmito Nugroho; Noormanto Noormanto; Nadya Arafuri; Indah Kartika Murni
Paediatrica Indonesiana Vol 60 No 5 (2020): September 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.5.2020.283-6

Abstract

Kawasaki disease (KD), or mucocutaneous syndrome, is an acute, systemic vasculitis of small- and medium-sized arteries that predominantly affects patients younger than five years.1 KD is the leading cause of childhood acquired heart disease in the developed world.2 The incidence in those aged under 5 years varies widely throughout the world, accounting for 8.4 per 100,000 in the UK, 17.5 to 20.8 per 100,000 in the USA, and 239.6 per 100,000 in Japan.2 The diagnosis of classic KD is based on the simultaneous presence of high fever for 5 or more days with at least four of five other symptoms (bilateral conjunctival hyperemia, ulcerations of the lips and inflammation of the oral cavity, polymorphous rash, edema and desquamation of the extremities, and cervical lymphadenopathy), or fever associated with less than 4 of the diagnostic criteria and echocardiographic abnormalities of the coronary arteries.3
Predictors of prolonged stay in the pediatric intensive care unit Yudha Fadhol Arafah; Indah Kartika Murni; Desy Rusmawatiningtyas
Paediatrica Indonesiana Vol 60 No 1 (2020): January 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.478 KB) | DOI: 10.14238/pi60.1.2020.37-41

Abstract

Background Prolonged stay in the pediatric intensive care unit (PICU) reflects not only disease severity and patient health status, but also the performance and quality of patient care. Objective To to determine whether surgical procedure, severe malnourishment, cardiovascular condition, sepsis, and ventilator use were the predictors of prolonged PICU stay. Methods This nested, case-control study was conducted with secondary data from medical records of pediatric inpatients at Dr. Sardjito General Hospital, Yogyakarta, Indonesia. We included pediatric patients aged 1 month-18 years treated in the PICU between 1 January - 31 December 2018. Predictors of prolonged stay were identified including surgical procedures, severe malnourishment, cardiovascular conditions, sepsis, and ventilator use. Logistic regression was used to identify independent predictors. Results Subjects' overall median age was 3.12 (IQR 0.76-18.8) years and the male to female ratio was 1:1. Median duration of ventilator use was 4 (IQR 1-21) days. The most common diagnosis was neurological disease (26.7%). Multivariate analysis showed that surgical procedure (OR 5.75; 95%CI 2.06 to 14.61) was statistically significant as an independent predictor of prolonged PICU stay. Conclusion Surgical procedure is the significant predictor of prolonged stay in PICU.
Co-Authors Desy Rusmawatiningtyas Indah Kartika Murni Nadya Arafuri Noormanto Noormanto Sasmito Nugroho