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Tjandra Husada
Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
Health Professions Medicine & Pharmacology

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Neonatal Tetanus Evaluation of Treatment and a Proposal for Classification of Severity Tjandra Husada; T. H. Rampengan; Ign. Harjanto; I. D. Arif; Muzief Munir
Paediatrica Indonesiana Vol 16 No 9-10 (1976): September - October 1976
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (879.665 KB) | DOI: 10.14238/pi16.9-10.1976.345-54

Abstract

An evaluation was made on 22 neonates with Tetanus Neonatorum (age 5 - 21 days), who were admitted to the Military Hospital, Teling, Manado, in 1973. Seventeen of our patients were babies born in their homes and were delivered by the "dukun kampong"; 5 babies were born in the maternity clinic and were helped by midwives. The therapy given were : Anti-Tetanus serum 10,000 U, single dose, given immediately on admission. Procain Penicilline 100,000 U/kg. b.w./day; i.m. divided into 2 equal doses for 10 days. Diazepam (valium) 5 mg./kg. b.w./day; oral, divided into 8 equal doses, and 2.5 mg, parenterally 4 times a day.
Failure of High Dosage Valium in the Treatment of Neonatal Tetanus Tjandra Husada; Muzief Munir
Paediatrica Indonesiana Vol 20 No 3-4 (1980): March - April 1980
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (449.504 KB)

Abstract

The fact that the mortality rate of neonatal tetanus is still high, and that the use of high dosage of valium has been reported to be of no side effect, encouraged the authors to use a high dosage of valium in the treatment of neonatal tetanus particularly in severe cases. This study was performed on 35 cases using 20-30 mg/kg bw/day of valium from July 1, 1976 through October 1977. The outcome of this study indicates that the treatment of neonatal tetanus using high dosage valium remained poor, where 22 out of 35 cases died (62.9%) with the following specifications: all of 6 mild cases survived, 2 out of 6 of moderate cases died, 20 out of 23 severe cases died. The authors believe that the simplest and the more effective way to overcome this disease is to give either tetanus prophylaxis to expectant mothers or 1500 U ATS prophylaxis to every newborn delivered by a traditional midwife (dukun bersalin).
Co-Authors I. D. Arif Ign. Harjanto Muzief Munir T. H. Rampengan