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Journal : Jurnal Syntax Fusion : Jurnal Nasional Indonesia

Hubungan Variasi Genetik Gen FADS pada Suku Sasak Terhadap Angka Kecukupan Gizi Ridha Sasmitha Ajiningrum; Luh Gde Sri Adnyani; Andi Agung Riatmojo; Vira Eka Trie Sanggita; Siti Rahmah
Jurnal Syntax Fusion Vol 2 No 01 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.137

Abstract

One of the macronutrients needed by the human body is fat. Fatty acids are divided into two, namely saturated and unsaturated fatty acids. Based on the source of unsaturated fatty acids are divided into two, namely non-essential and essential. Essential fatty acids consist of omega-3 and omega-6 which are part of PUFAs. To determine the relationship of genetic variation of the FADS gene to the nutritional adequacy of long-chain polyunsaturated fatty acids (LC-PUFA) in children of the Sasak ethnic. Systematic reviews were carried out through scientific journals, government guidelines, online portals for journal publications such as Medscape, Google Scholar, PubMed, and Science Direct, with the keyword “Polyunsaturated Fatty Acid (PUFA)” There was a significant relationship between the FADS2 index (DHA: EPA ratio) and MDI score (r = 0.648, p < 0.059) in AG but not in GG genotype. Two genotype models were found, namely homozygous major allele (GG) of rs 174468 which was dominant and heterozygous allele (AG) of Sasak ethnicity. The levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in infants in the Sasak ethnic were found to be higher than infants in other areas. Sasak ethnic children get EPA and DHA from breast milk which contains a lot of DHA. Sources of omega-3 and 6 on the island of Lombok are sea fish, seaweed, and full-blooded shellfish.
Ulkus Kronis: Mengenali Ulkus Dekubitus dan Ulkus Diabetikum Lalu Muhammad Hafizh Izuddin Alzamani; Mona Rianta Yolanda Marbun; Mutya Eka Purwanti; Rani Salsabilla; Siti Rahmah
Jurnal Syntax Fusion Vol 2 No 02 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i02.153

Abstract

Chronic ulcers become the factors of morbidity and mortality with an increasing prevalence. The causes of chronic ulcers are venous dysfunction, diabetes mellitus, infection, peripheral neuropathy, stress, and atherosclerosis. Decubitus ulcers are caused by irreversible mechanical pressure on the soft tissue, usually on prominent bones. In addition, the diabetic ulcer is a complication of diabetes mellitus that causes an increase in overall morbidity in patients. Diabetic ulcers can form due to a lack of glycemic control, neuropathy, peripheral vascular disease, or inadequate treatment of wounds on the feet. This article aims to review Chronic Ulcers, specifically Decubitus Ulcers,and Diabeticum Ulcers. Source searches were carried out on online portals for journal publications such as Google Scholar (scholar.google.com) and NCBI (ncbi.nlm.nih.gov), with the keyword Globally, the incidence of pressure ulcers reaches 33% and diabetic ulcers reach 15% of all diabetics. In dealing with chronic ulcers, in general, there is the main principle, namely TIME. The acronym TIME stands for four things to pay attention to, namely: T (Tissue) for a wound that is not feasible or deficient; I (Infection) for with infection/inflammation; M (Moisture) for wound moisture imbalance, which have to be corrected; E (Edge) for a wound where the edge does not cross into it.