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All Journal KESANS : International Journal of Health and Science
Putri Nurhayati
Universitas Mataram
Chemistry Health Professions Medicine & Pharmacology Physics Public Health

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Journal : KESANS : International Journal of Health and Science

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Pediatric Acute Respiratory Distress Syndrome (PARDS) On Pediatric COVID-19 Patients Siti Rahmah; Lalu Wahyu Alfian Muharzami; Lastri Akhdani Almaesy; Putri Nurhayati; Ridha Sasmitha A
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 2 (2021): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.704 KB) | DOI: 10.54543/kesans.v1i2.8

Abstract

At the end of 2019, there was a pandemic happening in the world, called the novel Coronavirus disease-19 (COVID-19). Various spectrums of disease from COVID-19, one of which is ARDS. The incidence of COVID-19 in children is not as much as in adults. However, in children under one year of age it can get worse. The main characteristic of worsening infection is the occurrence of ARDS. Objective: To find out the best treatment for PARDS in COVID-19 patients. Method: The writing of this article uses various sources from scientific journals to government guidelines and related institutions. Search articles using the keywords “Acute Respiratory Distress Syndrome”, “ARDS”, “Pediatric Respiratory Distress Syndrome”, “PARDS”, and “PARDS on COVID-19” Result and Discussion: PARDS was defined based on PALICC in 2015. Pathophysiology of PARDS in COVID-19 patients is still unclear. However, there is a theory that explains the way SARS-Cov-2 enters cells, namely through membrane fusion, giving rise to ARDS. The difference in handling PARDS for COVID-19 patients is that the handling technique is more alert to the risk of aerosols. Conclusions: There are differences in the handling of PARDS for COVID-19 patients in the technique by reducing the risk of virus transmission by preventing leakage when using a ventilator and using a bacterial/virus filter, as well as rescuers and staff using complete PPE during the procedure.
Poteng Local Food Potential with isolate Lactobacillus Plantarum in Preventing Depression Putri Nurhayati; Muhammad Sulthan Ardhi P.F; Abiyyu Didar Haq
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 3 (2021): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i3.31

Abstract

Depression is a global problem whose symptoms are easier to observe than cure. With a fairly high prevalence in Indonesia, which is up to 6.1% in 2018, this problem practically does not only affect the sufferer but also has an impact on the people around him which in turn will further reduce the quality of life of the sufferer. Lombok Island has a local food called poteng which is the result of fermented sticky rice. Poteng is able to act as a probiotic because it contains Lactobacillus plantarum. Probiotics can play a role in helping people with depression with the Gut Brain Axis mechanism by reducing Interleukin-6, increasing gamma-Aminobutyric Acid, and influencing Vitamin D and its receptors. In a depressed state, Interleukin-6 was observed to increase whereas GABA was observed to decrease. The Gut Brain Axis mechanism affects depression through neuroanatomical pathways, regulation of microbial metabolites (Short-Chain Fatty Acid), Tryptophan metabolism, and Immune Regulation.
Co-Authors Abiyyu Didar Haq Lalu Wahyu Alfian Muharzami Lastri Akhdani Almaesy Muhammad Sulthan Ridha Sasmitha A Siti Rahmah