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Journal : Jurnal Syntax Fusion : Jurnal Nasional Indonesia

Atopic Eczema Dan Komorbiditas Kondisi Psikologis: Bagaimana Hubungan Dan Tatalaksananya Ninda Nurkhalifah; Ridha Sasmitha Ajiningrum; Ilma Basyir; Genta Atsani; Zanetha Ilawanda
Jurnal Syntax Fusion Vol 2 No 01 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.135

Abstract

Atopic eczema or atopic dermatitis (AD) is a chronic recurrent inflammatory skin disease. Atopic dermatitis is almost 20% in children and 10% in adults. The etiology of atopic dermatitis is genetic and environmental factors that cause abnormalities in the epidermis and immune system. To determine the psychological comorbidities of atopic dermatitis patients and their management. The writing of this article includes various sources originating from scientific journals on online portals of journal publications such as Medscape, Google Scholar, PubMed, and NCBI, with the keyword “Eczema Atopic” Individuals with AD are at risk for psychological disorders. Psychiatric comorbidities that can occur in AD patients are depression, anxiety, stress, behavioral disorders, and psychosis. Atopic dermatitis has a major impact on the mental health and quality of life of individuals with AD as a result of intense itching, unpredictable disease, and feelings of disability caused by skin lesions. Individuals with atopic eczema are more likely to experience depression and anxiety because of the effects of itching and discomfort, disability, and perceived social stigmatization. Lack of sleep due to itching at night can increase the risk of mental disorders. This causes individuals with AD to have a lower quality of life and higher stress levels than healthy individuals.
Hubungan Variasi Genetik Gen FADS pada Suku Sasak Terhadap Angka Kecukupan Gizi Ridha Sasmitha Ajiningrum; Luh Gde Sri Adnyani; Andi Agung Riatmojo; Vira Eka Trie Sanggita; Siti Rahmah
Jurnal Syntax Fusion Vol 2 No 01 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.137

Abstract

One of the macronutrients needed by the human body is fat. Fatty acids are divided into two, namely saturated and unsaturated fatty acids. Based on the source of unsaturated fatty acids are divided into two, namely non-essential and essential. Essential fatty acids consist of omega-3 and omega-6 which are part of PUFAs. To determine the relationship of genetic variation of the FADS gene to the nutritional adequacy of long-chain polyunsaturated fatty acids (LC-PUFA) in children of the Sasak ethnic. Systematic reviews were carried out through scientific journals, government guidelines, online portals for journal publications such as Medscape, Google Scholar, PubMed, and Science Direct, with the keyword “Polyunsaturated Fatty Acid (PUFA)” There was a significant relationship between the FADS2 index (DHA: EPA ratio) and MDI score (r = 0.648, p < 0.059) in AG but not in GG genotype. Two genotype models were found, namely homozygous major allele (GG) of rs 174468 which was dominant and heterozygous allele (AG) of Sasak ethnicity. The levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in infants in the Sasak ethnic were found to be higher than infants in other areas. Sasak ethnic children get EPA and DHA from breast milk which contains a lot of DHA. Sources of omega-3 and 6 on the island of Lombok are sea fish, seaweed, and full-blooded shellfish.