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All Journal KESANS : International Journal of Health and Science
Akbar Dwi Juliardi NR
Universitas Mataram
Chemistry Health Professions Medicine & Pharmacology Physics Public Health

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Neuropathogenesis of Human Rabies Inas Hanan Farihah; Akbar Dwi Juliardi NR; Baiq Ananda Audia Arsiazi; Cahya Nabila; Puput Anggrayani
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 4 (2022): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i4.37

Abstract

Rabies is an acute infection that occurs in the central nervous system caused by a virus from the Rhabdoviridae family and the Lyssavirus genus that can be transmitted by dogs, cats, monkeys, bats, civets, and wolves. The purpose of writing this literature review is to determine the definition, epidemiology, neuropathogenesis and the role of neurotransmitters, clinical features, diagnosis, and management of rabies. The method used in writing this journal is a literature review, using literature searching. Search the library using website-based search tools, namely Google and Google Scholar using the keywords Rabies, Human Rabies, and Neuropathogenesis of Human Rabies. Free full text English and Indonesian publications. The journals selected in this literature review are 12 journals published between 2015-2021. Rabies infection begins with the transfer of viral microorganisms into the bite wound through the saliva of an infected animal. Rabies virus receptors consist of nicotinic acetylcholine receptors, Neural cell adhesion molecules (NCAM), and Nerve Growth Factor (NGF). Virus replication occurs in skeletal muscle and spreads via motor or sensory nerves to the spinal cord and brain. The virus binds to the nicotinic acetylcholine receptor via the neuromuscular route. There are 3 neurotransmitters that play a role in the neuropathogenesis of rabies, namely acetylcholine, serotonin, and GABA.
Characteristics of Astrocytoma in Indonesia Akbar Dwi Juliardi NR
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 4 (2022): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i4.38

Abstract

Astrocytoma is a primary brain tumor originating from astrocyte cells. The study was conducted using scientific literature review methods from various sources such as google search and google scholar with relevant keywords such as “prevalensi astrositoma di indonesia”, “kejadian astrositoma di indonesia”, "prevalence of astrocytoma in Indonesia", and "epidemiology primary brain tumor in Indonesia". After reading the titles and abstracts of the articles found, there were five research articles that met the criteria. From this literature study, there were 269 cases of astrocytoma in several hospitals in Indonesia in 2007-2018. At RSUP Dr. Hasan Sadikin Bandung in 2007–2009 astrocytomas were most commonly found in patients aged 20–34 years. In 2010–2012 astrocytoma was most commonly found in patients aged 31–40 years. And in 2013-2016 astrocytomas were most commonly found in patients aged 46 to 55 years. While at RSUP Dr. Wahidin Sudirohusodo in 2016 most astrocytomas were found in patients aged 20-29 years. Astrocytoma at RSUP Dr. Hasan Sadikin Bandung in 2007-2009 was mostly located in the frontal area, in 2010-2012 astrocytoma was mostly located in the cerebral hemispheres, and in 2013-2016 astrocytoma was mostly located in the cerebellum. At RSUP Dr. Wahidin Sudirohusodo astrocytoma mostly located in frontotemporal. At RSUP Dr. Hasan Sadikin Bandung astrocytoma is more often found in men, while in RSUP. Dr. Wahidin Sudirohusodo astrocytoma is more common in female patients.
Co-Authors Baiq Ananda Audia Arsiazi Cahya Nabila Inas Hanan Farihah Puput Anggrayani