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Zola Efa Harnis
Institut Kesehatan Delihusada
Health Professions Public Health Veterinary

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FORMULATION OF DRAWINGS (DRYMOGLOSSUM PILOSELLOIDES L. PRESL) ETHANOL EXTRACT OF ACNE GEL ON THE GROWTH OF THE BACTERIA PROPIONIBACTERIUM ACNES Zola Efa Harnis; Nina Irmayanti Harahap; Rika Puspita Sari; Sarviana Lubis
Jurnal EduHealth Vol. 12 No. 02 (2022): : March, Jurnal EduHealth
Publisher : Sean Institute

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Abstract

Dragon scales (Drymoglossum piloselloides L. Presl) is a plant that has antibacterial activity against the bacteria Propionibacterium acnes and Staphylococus aureus, Bacillus subtilis, Escherichia coli, and Streptococcus pneumonia. The content of compounds that act as antibacterial are saponins, polyphenols, essential oils, sterols / triterpenes, phenols, flavanoids, sugars and tannins. This study aims to make a formula of dragon scales ethanol extract gel against the growth of propionibacterium acnes bacteria. The method used in this study was experimental laboratory. The formulation of dragon scales ethanol extract gel is made with a concentration variation of 5%, 10%, 15%. Antibacterial activity test is carried out with diffusion agar.
FORMULATION OF HAND SANITIZER GEL PREPARATION COMBINATION OF NEMBA LEAF (AZADIRACHTAINDICAA.JUSS) ETHANOL EXTRACT OF AND EXTRACT OF ALOE VERA (ALOE VERA)AGAINS STAPYLOCOCCUCAUREUS BACTERIA Rika Puspita Sari; Zola Efa Harnis Harnis; Nina Irmayanti Harahap; Rissa Dewi Ramadhani
Jurnal EduHealth Vol. 12 No. 02 (2022): : March, Jurnal EduHealth
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (644.124 KB)

Abstract

The use of hand antiseptics in the form of gel preparations which are more popular with the namepreparations hand sanitizer usually contain antiseptics in the form of synthetic chemicals which are relatively expensive and often cause skin health problems, such as dry skin. The leaves of the neem plant and aloe vera gel have been shown to be able to treat several diseases, one of which is being able to be a companion drug for antibacterial treatment. The method used in this research is experimental method because it is intended to determine the effect or relationship between the independent variables called treatment factors, namely thegel formulation Hand Sanitizer from a combination of neem leaves and aloe vera gel with concentrations of 5%, 10%, and 15%, with the dependent variable called the observation factor, namely the test. Organoleptic, pH, homogeneity, dispersion test, irritation test and antibacterial activity tes. The results obtained from this study are that neem leaf ethanol extract and aloe vera gel can be formulated intopreparations hand sanitizer gelwith concentrations of 5%, 10% and 15%, with homogeneous preparations, pH around 6.68-7.03, with dispersion ranges from 4.4cm - 5.5 cm, and stable at 4 weeks of storage.. Results preparations hand sanitizers containing ethanol extract of neem leaves 15% provides a strong barrier against Staphylococcus aureus was 13.80 ± 0.29 mm.
Co-Authors Nina Irmayanti Harahap Rika Puspita Sari Rissa Dewi Ramadhani Sarviana Lubis