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All Journal Farmasis: Jurnal Sains Farmasi
Darini Kurniawati
Program Studi Sarjana Farmasi, Universitas Sari Mulia, Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

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Formulasi dan Uji Aktivitas Antiseptik dari Bahan Alam Kulit Jeruk Nipis, Daun Sirih dan Tanaman Bundung terhadap Staphylococcus aureus dan Candida albican Darini Kurniawati
FARMASIS: Jurnal Sains Farmasi Vol 2 No 1 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Program Studi Farmasi Fakultas Sains Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i1.3622

Abstract

The use of antiseptics is highly recommended when there is a disease epidemic, even like the current Corona Virus Disease (Covid-19) pandemic, because it can slow the spread of the disease or break the chain of disease spread. The sheath made of lipids is easily damaged by fatty solvents (soap, detergent, alcohol> 60%, chloroform, ether), making the covid-19 virus unable to infect and reproduce. The purpose of this study was to determine the ability to inhibit or kill Staphylococcus aureus and Candida albican bacteria from a combination of betel leaf (Piper betle L) plant extracts, lime peel (Citrus aurantifolia) and bundung plants (Actinuscirpus grossus) from the formulation F20% w/v, F30% w/v, 40% w/v and 50% w/v. The research method was experimental by making test formulations with concentrations of F1 20%, F2 30%, F3 40% and F4 50% and tested against Staphylococcus aureus and Candida albican bacteria with the disk diffusion method. The results showed that all test formulations had inhibitory power against Staphylococcus aureus and Candida albican and were very strong at 50% formulations, while the antiseptic activity in the formulations was 40%.
Perilaku dan Tingkat Pengetahuan Masyarakat Desa Teluk Kepayang terhadap Swamedikasi Maag Darini Kurniawati; Siti Rudiah; Nurul Hidayah
FARMASIS: Jurnal Sains Farmasi Vol 3 No 1 (2022): FARMASIS: Jurnal Sains Farmasi
Publisher : Program Studi Farmasi Fakultas Sains Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v3i1.4646

Abstract

Berbagai jenis obat tanpa resep dibeli konsumen untuk pengobatan sendiri. Berbagai faktor yang berhubungan dengan pengobatan sendiri, seperti iklan di televisi, biaya, dan tingkat pendidikan masyarakat. Pengobatan sendiri harus dilakukan secara benar dan rasional agar tidak terjadi penyakit baru yang timbul akibat penggunaan obat yang tidak tepat. Desain penelitian yang digunakan dalam penelitian ini adalah observasional analitik (non-eksperimental) dengan menggunakan desain penelitian cross sectional atau studi potong lintang. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan pengetahuan dan perilaku masyarakat tentang pengobatan sendiri maag di Desa Teluk Kepayang. Hasil tingkat pengetahuan masyarakat cukup dengan jumlah 37 orang (56,1%), tingkat perilaku pengobatan sendiri maag 60 orang (90%), Tidak ada hubungan antara pengetahuan dengan perilaku pengobatan sendiri maag karena hasil nilai signifikansinya adalah 0,892 (> 0,05). Berdasarkan hasil penelitian yang dilakukan di Desa Teluk Kepayang dapat disimpulkan bahwa tingkat pengetahuan masyarakat lebih memiliki pengetahuan yang cukup tentang pengobatan sendiri maag dan perilaku pengobatan sendiri maag pada masyarakat memiliki tingkat perilaku yang lebih rendah. Faktor yang berhubungan dengan tingkat pengetahuan masyarakat tentang pengobatan sendiri maag adalah faktor usia dan pendidikan.
Pengembangan Produk Sabun Cair Herbal terhadap Staphylococcus aureus dan Escherichia coli: Product Development of Herbal Liquid Soap against Staphylococcus aureus and Escherichia coli Darini Kurniawati
FARMASIS: Jurnal Sains Farmasi Vol 3 No 2 (2022): Farmasis : Jurnal Sains Farmasi
Publisher : Program Studi Farmasi Fakultas Sains Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v3i2.5659

Abstract

Abstrak Mencuci tangan dengan sabun bisa memutus mata rantai penyebaran Covid-19. Saat ini sabun cair lebih disukai karena lebih praktis digunakan. Oleh karena itu, kami ingin meneliti lebih lanjut efektifitas sabun cair herbal antiseptik pengembangan formulasi antiseptik herbal dari penelitian sebelumnya. Tujuan: Mengetahui efektivitas formulasi kombinasi herbal daun sirih, kulit jeruk nipis dan tanaman bundung dalam produk sabun cair antiseptik Metode: True eksperimental, kelompok mencuci tangan dengan sabun cair herbal, kelompok kontrol , uji daya hambat terhadap Staphylococcus aureus dan Escherichia colli beserta evaluasi ph, organoleptik, stabilitas busa, kadar air, asam lemak bebas dan alkali bebas. Hasil: Bentuk cair, bau lemon dan warna kuning, busa 15 – 70 mm, pH 10, kadar air 52%, asam lemak bebas 0,05%, alkali bebas 0,091%. penurunan angka kuman sebesar 90,5% dan diperkuat dengan analisa bivariat menggunakan Paired T tes diperoleh nilai signifikansi 0,0001 (<0,05). uji antibakteri dengan metode dilusi dan dilanjutkan daya hambat mikroba diperoleh KHM. Terhadap Staphylococcus aureus KHM pada konsentrasi 25% dan KBM pada konsentrasi 25%.Terhadap Escherichia colli KHM pada konsentrasi 30% dan KBM pada konsentrasi 25% . Kesimpulan: : Sabun cair herbal daun sirih, kulit jeruk nipis dan tanaman bundung sesuai standar SNI sabun cair yang dipersyaratkan, efektif menurunkan angka kuman dan ditemukan KHM serta KBM pada semua mikroba yang diujikan. Kata kunci : sabun cair _herbal_antiseptik Abstract Washing hands with soap can break the chain of the spread of Covid-19. Currently liquid soap is preferred because it is more practical to use. Therefore, we would like to further investigate the effectiveness of herbal antiseptic liquid soap in developing herbal antiseptic formulations from previous studies. Objective: To determine the effectiveness of the herbal combination formulation of betel leaf, lime peel and bund plants in antiseptic liquid soap. Methods: True experimental, hand washing group with herbal liquid soap, control group, test of inhibition against Staphylococcus aureus and Escherichia colli along with evaluation of pH, organoleptic, foam stability, moisture content, free fatty acids and free alkali. Results: Liquid form, lemon odor and yellow color, foam 15 – 70 mm, pH 10, water content 52%, free fatty acids 0.05%, free alkali 0.091%. decrease in germ numbers by 90.5% and strengthened by bivariate analysis using Paired T test obtained a significance value of 0.0001 (<0.05). antibacterial test by dilution method and continued with microbial inhibition obtained MIC. Against Staphylococcus aureus MIC at a concentration of 25% and MBC at a concentration of 25%. Against Escherichia colli MIC at a concentration of 30% and MBC at a concentration of 25%. Conclusion:Betel leaf herbal liquid soap, lime peel and bundung plants according to the required SNI standard for liquid soap, effectively reduce the number of germs and MIC and KBM were found in all tested microbes. Keywords: liquid soap _herbal_antiseptic
Tingkat Pengetahuan dan Perilaku Swamedikasi Batuk Pilek Mahasiswa Farmasi Angkatan 2019 Universitas Sari Mulia dengan Metode TPB Darini Kurniawati; Estyvania Nur Charmelya; Hansel Hens Tangkas; Pungky Angeliana Putri Panjaitan
FARMASIS: Jurnal Sains Farmasi Vol 3 No 2 (2022): Farmasis : Jurnal Sains Farmasi
Publisher : Program Studi Farmasi Fakultas Sains Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v3i2.5653

Abstract

AbstractCoughs and colds are a response the body created to get rid of foreign objects, including viruses, dust, mucus, and other small particles that try to contaminate the respiratory tract starting from the throat to the lungs. Cough symptoms can be treated with self-medication, which is a self-medication process carried out by a person starting from the introduction of complaints or symptoms to the selection and use of drugs. There are methods that can beused to treat coughs and colds, namely pharmacological methods (drug therapy) and nonpharmacological methods (non-drug therapy). The theory used can be observed, namely the method of Theory of Planned Behavior or TPB (Theory of Planned Behavior). The purpose of this activity is to increase students' knowledge and skills in dealing with coughs and colds. So that it is expected to provide information and treatment in making efforts to prevent cough and cold symptoms. This type of research is observational research with descriptive research methods. The approach used is cross sectional. The level of knowledge of the 2019 batch of pharmacy students at Sari Mulia University Banjarmasin about self-medication for cough and cold with a good category of 23 respondents, 22 %, with a sufficient category of 63 respondents (62 %), and a less category as many as 16 respondents,  16 % . From these results, it is hoped that the institution will further deepen and evaluate after learning or lecturesin order to maximize the material obtained, it is hoped that students apply and relearn what they have learned so that their knowledge is good, and it is also hoped that future researchers can investigate further about rationality. self-medication actions taken by students.
Co-Authors DWI SURYANTO Estyvania Nur Charmelya Hansel Hens Tangkas Pungky Angeliana Putri Panjaitan Siti Rudiah