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Efektivitas Rebusan Daun Muntingia Calabura L Segar dan Kering sebagai Penurun Hiperglikemia pada Mencit Hasma Hasma; Suryanita Suryanita
Jurnal Kesehatan Manarang Vol 6 No 2 (2020): Desember 2020
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v6i2.333

Abstract

Muntingia Calabura L is one of the plants that can reduce hyperglycemia which has an antioxidant effect. This effect is due to its high content of flavonoids that can inhibit the oxidation process. This study aims to determine the effectiveness of fresh and dry cherry leaves decoction in reducing hyperglycemia in mice (Mus-Musculus). The study used a laboratory-experimental design with a glucose induction method using 24 male mice divided into eight groups: positive control (metformin), negative control (aquadest), three groups of cherry leaves (fresh and dry) with a concentration of 5%, 10%, and 15%. Each group consisted of 3 male mice. The results showed that an effective decrease was in the positive control of metformin 113 mg/dl, following a 15% concentration in fresh leaves 88 mg/dl, and 15% dry leaves 79 mg/dl. The conclusion in this study was that there was no significant difference between the stew of fresh cherry leaves and dried cherry leaves. The decoction of fresh cherry leaves and dried cherry leaves were both effective in reducing mouse hyperglycemia at a concentration of 15%. It is suggested for further research to use fresh and dry cherry leaf extract samples using other methods.
Identifikasi Senyawa Metabolit Sekunder Ekstrak Etanol Kulit Buah Pisang Kepok (Musa paradisiaca L) dengan Metode KLT Hasma Hasma; Winda Winda
Jurnal Kesehatan Manarang Vol 5 No 2 (2019): Desember 2019
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.365 KB) | DOI: 10.33490/jkm.v5i2.176

Abstract

Indonesia is a country that is rich in abundant natural plants by having various types of plants which have medicinal properties and are used by some people as traditional medicines. One use of traditional medicine used by the community is the banana plant. So far the community only uses bananas, limited to the use of their fruit, then the banana peel after consumption is only disposed of as waste that is not used optimally by the community. This study aims to identify the chemical compounds found in the skin of Kepok Banana (Musa paradisiaca L) taken from the pioneer road in the city of Makassar. This identification is carried out using the Thin Layer Chromatography (TLC) method and chemical reagents. Kepok banana peel extract (Musa paradisiaca L.) is made using maceration method, because the method is not only simple, the equipment used is simple, easy to work on, can also avoid damage to compound components due to heat. The yield of Rendamen obtained was 12.06%. Identification was done using Silica Thin Layer Chromatography GF254 with N-hexane eluent: ethyl acetate (6: 4) eluents obtained 5 stains on 366 nm UV light, namely alkaloids with orange blotches with Rf value (0.13), saponins with blemishes. purple Rf value (0.92), flavonoids with yellow spots Rf values ​​(0.33) and tannins with blackish orange patches Rf values ​​(0.65). Based on testing using chemical reagents obtained positive results saponins, flavonoids, tannins and alkaloids. The conclusion of the study showed that the Kepok banana peel extract taken on the pioneering road of Makassar city contained alkaloids, saponins, flavonoids and tannins.
Uji Efek Antioksidan Formulasi Sediaan Sirup Ekstrak Etanol Kulit Buah Jeruk Bali (Citrus Maxima Merr.) Terhadap Malondialdehid Tikus Putih (Rattus Novergicus) Yang Diinduksi Karbon Tetraklorida Suryanita Suryanita; Hasma Hasma
Media Kesehatan Politeknik Kesehatan Makassar Vol 16, No 1 (2021): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v16i1.1836

Abstract

Free radicals are any molecule or atom that is unstable because it has one or more unpaired electrons. Free radicals that are formed in the body will produce new free radicals through a chain reaction which eventually increases in number and attacks the body's cells so that tissue damage will occur, therefore antioxidants are needed from outside to neutralize free radicals, the salute is grapefruit peel (Citrus maxima Merr.) This study aims to determine the antioxidant activity of the ethanol extract syrup of grapefruit peel against levels of Malondialdehyde (MDA) blood plasma of male white rats induced by carbon tetrachloride (CCl4). The stages of this study were the first to make a skin extract syrup. grapefruit peel containing 1% extract (F1), 2% extract (F2), 3% extract (F3), and without grapefruit peel extract (F4) as negative control; Furthermore, testing the stability of the syrup preparations before and after storage was accelerated for 12 cycles, and finally the syrup with the best stability was tested for its lipid peroxidation inhibition activity in vivo with blood plasma MDA levels in rats induced by Carbon Tetrachloride. The results showed the results of the syrup stability test. indicates that F3 has the best stability. As for the in vivo test results, F3 showed a decrease in the MDA level of blood plasma in rats which was significantly different from the negative control. The grapefruit peel significantly decreased the MDA level of the rat blood plasma with a  value p<0.05. Keywords : Free radicals, Grapefruit Peel, Antioxidant, Syrup Preparation, Malondialdehyde (MDA)
Formulasi Sediaan Sabun Mandi Padat Dari Ekstrak Etanol Daun Kedondong (Spondias pinnata (L.f) Kurz) Hasma Hasma; Erna Kadrianti
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13513

Abstract

Healthy skin is an element of female beauty. The thing that supports it is with cosmetics. The rise of the "back to nature" lifestyle has increased public confidence in cosmetics with natural ingredients. Cosmetics with natural ingredients are claimed to be safer to use on the skin than cosmetics using synthetic chemical compounds. Research has been carried out with the title "Formulation of Solid Bath Soap from Ethanol Extract of Kedondong Leaves (Spondias pinnata (L.f) Kurz)". This study aims to determine whether the formulation of solid bath soap from Kedondong (Spondias pinnata (L.f) Kurz) Leaf Ethanol Extract meets the criteria for quality requirements of pH, water content and high foam. The extract concentrations used were F1(3.5), F2 (7) and F3 (10.5). From the results of the research that has been carried out, it is obtained that the solid soap preparations F1 (3.5), F2 (7) meet the quality criteria test for pH, water content and foam height both before and after the cycling test. While the soap in FIII (10.5) met the water content and high foam test, but did not meet the pH quality standard for solid soap. Based on the results of this study, it can be concluded that from the three formulas above, the soap in FI and FII is a soap that meets the quality standard test of pH, water content and high foam. While the soap in FIII is soap that does not meet the required solid soap pH quality standard.
Formulasi Sediaan Sabun Cair Dari Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Andi Nurpati Panaungi; Hasma Hasma
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.16483

Abstract

Cherry leaves (Muntingia calabura L.) is a plant that has many medicinal properties. One part of the plant that is widely used is the leaf which contains flavonoid compounds, saponins and tannins found in cherry leaves so that it has strong antioxidant activity which can be efficacious as skin lightening and antiseptic. This study aims to formulate liquid soap ethanol extract of cherry leaves (Muntingia calabura L.). This type of research was carried out in an experimental laboratory using the maceration method to produce a thick extract from cherry leaves. There were 3 formulas for liquid soap with different extract concentrations, namely FI (3%), FII (6%), and FIII (9%). Tests for liquid soap preparations of cherry leaves extract include organoleptic tests (shape, smell, color), homogeneity test, pH test, foam height test, and water content test. From the results of research conducted on organoleptic tests, FI(3%) has has a liquid form, brown color and a distinctive aroma. and FIII(9%) has a slightly thick liquid form, dark brown color, and a distinctive aroma. In the homogeneity test on all formulas get homogeneous results. In the pH test FI(3%) with a pH of 8, FII(6%) and FIII(9%) with a pH of 9. In the FI(3%) foam height test with a foam height of 8.5 cm, FII(6%) with a foam height 7.7 cm, FIII(9%) with foam height 7.1 cm. on the water content test FI(3%) with a water content of 56.25%, FII(6%) with a water content of 53.75%, FIII(9%) with a water content of 48.00%. So it can be concluded that the liquid soap formulations FI(3%), FII(6%), and FIII(9%) meet the requirements set by SNI in every test of liquid soap preparations. So that cherry leaf extract can be formulated into liquid soap with extract concentrations of 3%, 6% and 9%.
Identifikasi Senyawa Metabolit Sekunder Ekstrak Etanol Kulit Buah Pisang Kepok (Musa paradisiaca L) dengan Metode KLT Hasma Hasma; Winda Winda
Jurnal Kesehatan Manarang Vol 5 No 2 (2019): Desember 2019
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v5i2.176

Abstract

Indonesia is a country that is rich in abundant natural plants by having various types of plants which have medicinal properties and are used by some people as traditional medicines. One use of traditional medicine used by the community is the banana plant. So far the community only uses bananas, limited to the use of their fruit, then the banana peel after consumption is only disposed of as waste that is not used optimally by the community. This study aims to identify the chemical compounds found in the skin of Kepok Banana (Musa paradisiaca L) taken from the pioneer road in the city of Makassar. This identification is carried out using the Thin Layer Chromatography (TLC) method and chemical reagents. Kepok banana peel extract (Musa paradisiaca L.) is made using maceration method, because the method is not only simple, the equipment used is simple, easy to work on, can also avoid damage to compound components due to heat. The yield of Rendamen obtained was 12.06%. Identification was done using Silica Thin Layer Chromatography GF254 with N-hexane eluent: ethyl acetate (6: 4) eluents obtained 5 stains on 366 nm UV light, namely alkaloids with orange blotches with Rf value (0.13), saponins with blemishes. purple Rf value (0.92), flavonoids with yellow spots Rf values ​​(0.33) and tannins with blackish orange patches Rf values ​​(0.65). Based on testing using chemical reagents obtained positive results saponins, flavonoids, tannins and alkaloids. The conclusion of the study showed that the Kepok banana peel extract taken on the pioneering road of Makassar city contained alkaloids, saponins, flavonoids and tannins.
Efektivitas Rebusan Daun Muntingia Calabura L Segar dan Kering sebagai Penurun Hiperglikemia pada Mencit Hasma Hasma; Suryanita Suryanita
Jurnal Kesehatan Manarang Vol 6 No 2 (2020): Desember 2020
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v6i2.333

Abstract

Muntingia Calabura L is one of the plants that can reduce hyperglycemia which has an antioxidant effect. This effect is due to its high content of flavonoids that can inhibit the oxidation process. This study aims to determine the effectiveness of fresh and dry cherry leaves decoction in reducing hyperglycemia in mice (Mus-Musculus). The study used a laboratory-experimental design with a glucose induction method using 24 male mice divided into eight groups: positive control (metformin), negative control (aquadest), three groups of cherry leaves (fresh and dry) with a concentration of 5%, 10%, and 15%. Each group consisted of 3 male mice. The results showed that an effective decrease was in the positive control of metformin 113 mg/dl, following a 15% concentration in fresh leaves 88 mg/dl, and 15% dry leaves 79 mg/dl. The conclusion in this study was that there was no significant difference between the stew of fresh cherry leaves and dried cherry leaves. The decoction of fresh cherry leaves and dried cherry leaves were both effective in reducing mouse hyperglycemia at a concentration of 15%. It is suggested for further research to use fresh and dry cherry leaf extract samples using other methods.
Co-Authors Andi Nurpati Panaungi Erna Kadrianti Winda Winda