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All Journal Jurnal farmasi UIN Alauddin Makassar
Faridha Yenny Nonci
Jurusan Farmasi Fakultas Ilmu Kesehatan Universitas Islam Negeri Alauddin Makassar
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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UJI AKTIVITAS EKSTRAK ETANOL DAUN KEJIBELING (Strobilanthes crispus Linn) TERHADAPA PENURUNAN KADAR GLUKOSA DARAH PADA MENCIT JANTAN (Mus musculus) Faridha Yenny Nonci; Dwi Wahyuni Leboe; Armaila Armaila
Jurnal Farmasi UIN Alauddin Makassar Vol 4 No 1 (2016): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v4i1.2241

Abstract

Have been conducted a research examining the effect of ethanol extract of leaves kejibeling (Strobilanthes Crispus Linn) to degrade blood glucose level to male mice (Mus musculus). This aim of this research to find out the effect and to decide concentration of ethanol extract of leaves kejibeling can be used to degradation blood glucose level to male mice which induce by glucose 20 %. This research uses 15 male mice which devide by 5 group in treatment, where each experiment consist of 3 tail. Group of I was given Na CMC 1 % as negative control, group II, III, and IV were given of ethanol extract of leaves kejibeling with concentration 7,35 mg/ g BW, 14,7 mg/ g BW and 29,4 mg/ g BW and group V was given metformin 1,95 mg/ g BB mice as positive control. The result of the research was examined statistically by using method Group Random Design and continued Duncan test showed that effect of ethanol extract of leaves kejibeling with concentration 14,7 mg/ g BB do not differ reality was given metformin 1,95 mg/ g BB male mice, can degrade the rate of blood glucose. 
UJI AKTIVITAS ANTIMIKROBA HASIL FRAKSINASI EKSTRAK ETANOL DAUN PATIKALA (ETLINGERA ELATIOR) TERHADAP BEBERAPA MIKROBA UJI Faridha Yenny Nonci; A Tenriugi Daeng; Hasnia A
Jurnal Farmasi UIN Alauddin Makassar Vol 4 No 2 (2016): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v4i2.2244

Abstract

The purpose of this study was to determine the activity of ethanol extract of leaves patikala fraction (Etlingera elatior) as an antimicrobial in some microbes and identify the components of compounds in the leaves patikala which acts as an inhibitor of the microbes. The research was done by using KLT-Bioautografi. Simplicia leaves patikala macerated with maceration method stratified by using solvent n-hexane and ethanol 96%, then the test screening of bacteria which then extract fractionation actively performed by the method of KCV (Vacuum Liquid Chromatography), chromatographic separation of compounds results then carried TLC -Bioautografi are placed on the surface of the solidified medium. After 15-30 minutes plates (chromatogram) is appointed and removed from the medium, were incubated for 1 x 24 hours at 37 ° C for bacteria and 3 x 24 hours at room temperature for mushrooms. Results showed that the microbes could be reversed after tested KLT- Bioautografi there are 5 bacterium is Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Streptococcus mutans, and Pseudomonas aeruginosa. Further quantitative research to determine the level of effectiveness of the results of the leaf fraction patikala to determine the value of MIC (Minimum Inhibitory Concentration) and the sensitivity of the most active fraction against microbes Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Streptococcus mutans, and Pseudomonas aeruginosa. 
Co-Authors A. Tenriugi Daeng Pine Armaila Armaila Dwi Wahyuni Leboe Hasnia A