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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Marthino Robinson
Unknown Affiliation
Medicine & Pharmacology

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Mortality Risk Factors in Acute Upper Gastrointestinal Bleeding Marthino Robinson; Ari Fahrial Syam; Murdani Abdullah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 1, April 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.025 KB) | DOI: 10.24871/131201237-42

Abstract

Background: Upper gastrointestinal bleeding (UGIB) is one of the emergency cases in gastroenterology. The mortality rate does not change in the last 4 decades, however, there is no precise data in Cipto Mangunkusumo Hospital. Identified risk factors are expected to increase early awareness and optimal planning in management of patients. This study was aimed to know the mortality risk factors in acute UGIB in Cipto Mangunkusumo Hospital. Method: Case control study was performed between August and December 2011 by collecting and studying medical records of acute UGIB patients who were admitted and hospitalized between January 2003 and June 2011 in Cipto Mangunkusumo Hospital. Cases were acute UGIB patients who passed away during hospitalization in that period of time. Controls were patients who did not pass away and hospitalize in same period (date/month/year index). Samples were taken randomly with the proportion of case and control 1 : 2. Bivariate analysis was perfomed by chi-square test and continued with multivariate analysis. Results: Study subjects consisted of 87 cases and 174 controls. Significant variables as risk factors were multiple co-morbidities (OR = 2.66; 95% CI = 1.21-5.85), recurrent bleeding (OR = 9.07; 95% CI = 3.87-21.26), decreased consciousness (OR = 7.60; 95% CI = 1.94-29.88), endoscopy not performed (OR = 11.95; 95% CI = 4.75-30.11), and sepsis (OR = 4.83; 95% CI = 2.03-11.48). Conclusion: Multiple co-morbidities, sepsis, decreased consciousness on hospital admission, and recurrent bleeding are mortality risk factors in acute UGIB. Mortality risk increases in patients, to whom endoscopy was not performed. Keywords: UGI bleeding, risk factors, mortality
Immunohistochemistry Profile of Breast Cancer Patients that Get Anthracyclin–Based Chemotherapy in RSUD Kota Bogor Robinson, Marthino; Atmakusumah, Tubagus Djumhana; Irawan, Cosphiadi; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
Publisher : UI Scholars Hub

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Abstract

Introduction. Breast cancer is the most prominent cancer and causing death in women. Treatment of breast cancer requires immunohistochemistry (IHC) to determine prognostic and predictive and imaging tests to determine staging. However, currently in Indonesia only 17 hospital can conduct IHC test. RSUD Kota Bogor like other Type B Hospital have no IHC test facilities. To fullfil that test, its important to refer patient to referal hospital. Because of limitation there are patients who did not do IHC test and continued get anthracycline chemotherapy. The objective of this research is to find out immunohistochemistry profile of breast cancer patients who received anthracycline-based chemotherapy in RSUD Kota Bogor. Methods. A descriptive retrospective study by collecting the breast cancer patients medical records was done since January 2014 to December 2017 in RSUD Kota Bogor. Results. Total of 174 subjects were include in this study which consist of 84 subjects (48%) with IHC test and 90 subjects (52%) without IHC test. The immunohistochemistry profile of breast cancer patients who received anthracycline-based chemotherapy since January 2014 to December 2017 in RSUD Kota Bogor were luminal type (64%), HER2-enriched (18%), and TNBC (18%). Conclusion. Luminal type is the most molecular subtypes in breast cancer patients who received anthracycline-based chemotherapy in RSUD Kota Bogor. However, because of limitation, since January 2014 to December 2017 only 48% of breast cancer patient that get anthracyclin chemotherapy who got IHC test in RSUD Kota Bogor.
Co-Authors Ari Fahrial Syam Atmakusumah, Tubagus Djumhana Cosphiadi Irawan Hamzah Shatri Murdani Abdullah Murdani Abdullah