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POTENSI AKTIVITAS ANTIMIKROBA MADU DAN HABBATUSSAUDA TERHADAP BAKTERI ESCHERICHIA COLI SECARA IN VITRO Alifia Ayu Delima; Utami Murti Pratiwi; Asriani
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 2 No 1 (2019): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v2i1.87

Abstract

Madu dan habbatussauda memiliki aktivitas antibakteri. Komponen yang terdapat di dalam madu antara lain keasaman, tekanan osmotik, dan hidrogen peroksida, asam aromatik serta omponen fenol juga berperan dalam aktivitas antibakteri. Sedangkan habbatussauda sendiri tannin, tymoquinon, thymol, a-pinene, p-cymene dengan cara menghambat pembentukan asam nukleat (RNA) dan sintesis protein yang berperan sebagai antibakteri dan antioksidan pada proses infeksi. Tujuan dari penelitian ini untuk mengetahui potensi antibakteri madu dan Habbatussauda terhadap bakteri Escherichia coli. Jenis penelitian ini adalah eksperimental dengan metode Post Test Only Control Group Design yang dilakukan secara in vitro. Hasil dari penelitian in vitro menunjukan bahwa terdapat pengaruh pemberian perlakuan madu, habbatussaudah dan kombinasi terhadap daya hambat pertumbuhan e-coli (<0.05).
POLA BAKTERI PADA ULKUS DIABETIKUM GRADE TIGA DI KLINIK LUKA DIABETES KOTA MAKASSAR Alifia Ayu Delima
KOLONI Vol. 1 No. 2 (2022): JUNI 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.981 KB) | DOI: 10.31004/koloni.v1i2.164

Abstract

Diabetes Mellitus is a global health problem and is one of the top 10 causes of death globally. One of the main complications of diabetes mellitus is diabetic ulcers. In Indonesia, the incidence of diabetic ulcers is reported to be around 12% and the risk of diabetic ulcers is around 55.4%. Incidence Infection is very common (40-80%) so it is a major cause of morbidity and mortality. Microbes in diabetic foot wounds can be monomicrobial and polymicrobial. This study aims to determine the bacterial pattern in diabetic ulcers. This study was conducted in vitro on isolates of third grade diabetic ulcers from 15 samples. Antimicrobial tests were carried out by inoculation on PCA (Plate Count Agar) and MSA (Mannitol Salt Agar) media. The results showed that the bacterial patterns seen were Staphylococcus haemolyticus, Staphylococcus aureus, Proteus Mirabilis, and Acinetobacter baumanii. In conclusion, the most common bacteria found in this study was Proteus mirabilis. Keywords: Diabetic ulcer, diabetes mellitus, bacterial pattern
POLA BAKTERI PADA ULKUS DIABETIKUM GRADE TIGA DI KLINIK LUKA DIABETES KOTA MAKASSAR Alifia Ayu Delima
KOLONI Vol. 1 No. 2 (2022): JUNI 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v1i2.164

Abstract

Diabetes Mellitus is a global health problem and is one of the top 10 causes of death globally. One of the main complications of diabetes mellitus is diabetic ulcers. In Indonesia, the incidence of diabetic ulcers is reported to be around 12% and the risk of diabetic ulcers is around 55.4%. Incidence Infection is very common (40-80%) so it is a major cause of morbidity and mortality. Microbes in diabetic foot wounds can be monomicrobial and polymicrobial. This study aims to determine the bacterial pattern in diabetic ulcers. This study was conducted in vitro on isolates of third grade diabetic ulcers from 15 samples. Antimicrobial tests were carried out by inoculation on PCA (Plate Count Agar) and MSA (Mannitol Salt Agar) media. The results showed that the bacterial patterns seen were Staphylococcus haemolyticus, Staphylococcus aureus, Proteus Mirabilis, and Acinetobacter baumanii. In conclusion, the most common bacteria found in this study was Proteus mirabilis. Keywords: Diabetic ulcer, diabetes mellitus, bacterial pattern