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Journal : SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN

Effect of Garlic (Allium sativum L.) Bulb Skin Extract on Urea and Creatinine Levels in Alloxan-Induced Hyperglycemia Wistar Rat Rosyid, Abdur; Wijayanti, Rina; Azizah, Nuzlil Laily Nur
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 7, No 1 (2016): January - June 2016
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (602.85 KB) | DOI: 10.30659/sainsmed.v7i1.1168

Abstract

Background: Garlic bulb skin extract contains flavonoid, alkaloid, saponin, quinone and polyphenol. Garlic bulb skin is a waste of garlic bulb which has not been optimally used so far for medical purpose. Objective: to discover the influence of garlic (Allium sativum L.) bulb skin extract on urea and creatinine levels in alloxan-induced hyperglycemia wistar rat. Methods: Experimental research using post-test control group design and its statistic analysis using Kruskal Wallis followed with Mann Witney test. The hyperglychemia rat is made by inducing alloxan at a single dose of 160 mg/kg bodyweight (BW) intraperitoneally. The garlic bulb skin extract doses used are 200mg/200gBW, 400mg/200gBW, and 800mg/200gBW for 14 days. The blood is sampled through vena orbitalis which is tested for its urea and creatinine levels.Results: The urea test in hyperglychemia rat administered with 200mg/200gBB garlic bulb skin extract (average urea level 88.87 mg/dL) has no differencce from the negative group (p>0.05), while the 400mg/200gBB and 800mg/200gBB doses (average urea levels 41.86 mg/dL and 41.96 mg/dL) show significant difference (p<0.05). The creatinine test shows significant influence (p<0.05) in extract dose of 400mg/200gBB (average creatinine level 1.16 mg/dL).Conclusion: it can be concluded that garlic bulb skin extract may have some influence in reducing urea level at 400mg/200gBB and 800mg/200gBB doses and creatinine level at 400mg/200gBB dose.
Analysis of Quality of Pharmacy Management Information System at Sultan Agung Islamic Hospital, Semarang Rosyid, Abdur; Marchaban, Marchaban; Pudjaningsih, Dwi
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 12, No 2 (2021): July-December 2021
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.622 KB) | DOI: 10.30659/sainsmed.v12i2.1828

Abstract

Introduction: Hospital is one of the important links in the service delivery system to the community so that the hospital is expected to provide information to support the provision of timely and accurate services. To improve the quality of hospital services, an up to date information system is needed. The user satisfaction on information system can be used to evaluate the quality of an organization's information system. Objective: to evaluate the quality of the pharmacy management information system (PMIS) at Sultan Agung Islamic Hospital (SAIH), Semarang, and determine the priority of area for improvements.Methods: In this cross-sectional qualititative study, the responses of all employees to questionnaire were obtained; these employees worked at the pharmacy of Sultan Agung Islamic Hospital in Semarang. The PIECES method was applied. The data analysis included gap and customer windowResults: The gap value on the dimension of performance, information, economic, control, efficiency, service was -1.10, -0.82, -0.28, -0.22, 0.01, -0.62, respectivelyConclusion: The user’s unfulfilled expectation on PMIS at SAIH including dimensions of performance, information, economy, control, service, and efficiency. Priority areas for quality improvement of PMIS at the Sultan Agung Islamic Hospital’s phamacy included the menu display, system responsiveness, the completeness of the system, no error occurs, the alert system of the drug stock, the responsiveness of the IT department to the problem of PIMS use.