Mia Munawarroh Yuniyanti
Department of Pharmacology and Therapy Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia

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Animal models in antihypertensive drug development research Dwi Aris Agung Nugrahaningsih; Mia Munawarroh Yuniyanti; Rahmi Ayu Wijayaningsih; Mosa Rini Nurul Hidayati; Setyo Purwono
Indonesian Journal of Pharmacology and Therapy Vol 1 No 2 (2020)
Publisher : Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFI) and Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.677 KB) | DOI: 10.22146/ijpther.585

Abstract

Hypertension is one of the most common diseases in the world. However, its pathogenesis is not fully understood and its treatment is not yet satisfying. Animal models of hypertension have been useful to understand the pathogenesis of hypertension and to test novel therapeutic agents. There are several kinds of hypertension animal models. Each model has different characteristics. Knowing the characteristic of each model is important to obtain valid research. This review will describe several available methods to develop animal model for hypertension.