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All Journal Sainstech Farma: Jurnal Ilmu Kefarmasian
Desy Muliana Wenas
Fakultas Farmasi, ISTN
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh Ekstrak Bonggol Pisang Kepok terhadap Kadar Gula Darah Tikus yang Diinduksi Aloksan Desy Muliana Wenas; Ika Septiana; Lisana Sidqi Aliya
SAINSTECH FARMA Vol 13 No 1 (2020): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : FAKULTAS FARMASI, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.132 KB) | DOI: 10.37277/sfj.v13i1.516

Abstract

Bonggol pisang telah dikenal berpotensi sebagai bahan obat tradisional. Tujuan penelitian yaitu untuk mengetahui kemampuan ekstrak bonggol pisang dalam mengurangi Kadar Gula Darah (KGD). Bonggol pisang kepok diekstrak menggunakan metode maserasi dengan pelarut etanol 70%, serta disiapkan dengan dosis konsentrasi 50, 100, 200 mg/200 g berat badan tikus yang diberikan secara oral pada tikus yang diinduksi dengan aloksan monohidrat (diabetes). Hasil penelitian menunjukkan ekstrak bonggol pisang kepok dapat mengurangi kadar gula dalam darah pada tikus yang telah diinduksi aloksan. Konsentrasi terbaik dalam penurunan KGD ialah 200 mg/200 g berat badan tikus, namun ekstrak bonggol pisang kepok masih kalah dibandingkan kontrol positif glibenklamid. Hasil penelitian tersebut dimaksudkan untuk membantu pengembangan produk obat antidiabetes yang berguna bagi bidang kesehatan di kalangan masyarakat.
Potensi Larvasida Ekstrak Daun Alpukat (Persea americana) terhadap Larva Nyamuk Aedes aegypti Desy Muliana Wenas; Muhammad Nur Fajrin; Subaryanti Subaryanti
Sainstech Farma: Jurnal Ilmu Kefarmasian Vol 16 No 1 (2023): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : LPPM, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

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Abstract

Avocado (Persea americana Mill.) leaves contain saponins, tannins, flavonoids and alkaloids that have potential as larvicides. The purpose of this study was to determine the larvicidal activity of ethanol extract of avocado (Persea americana) leaves against Aedes aegypti larvae. The test was carried out on 210 larvae which were divided intro 7 groups, namely group I, II, III, IV, V which were ethanol extract of avocado leaves with concentration of 0,1%; 0,5%; 1%; 1,5%; and 2%. Positive control (group VI) was given Temephos 0,01% solution and group VII as negative control was only given Aquadest. Each treatment groups were observed for larvae death and counted every hour for 24 hours. LC50 and LT50 values were calculated using probit analysis. The results showed that ethanol extract of avocado leaf had larvicidal activity against Aedes aegypti larvae with LC50 = 0,03% at 3 hours and LT50 = at 1 hour 42 minutes. The ethanol extract of avocado leaf had a potential as larvicidal against Aedes aegypti larvae.
Co-Authors Ika Septiana Lisana Sidqi Aliya Muhammad Nur Fajrin Subaryanti Subaryanti