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All Journal Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan Jurnal Medika Nusantara Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Observasi: Jurnal Publikasi Ilmu Psikologi Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Helsa Nasution
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Religion Arts Humanities Dentistry Economics, Econometrics & Finance Health Professions Nursing Physics Public Health Social Sciences Veterinary

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Journal : Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan

 1 
Efek Depresi terhadap Efektivitas Pengobatan Penyakit Crohn Helsa Nasution; M. Agung Rahmadi; Luthfiah Mawar; Milna Sari
Jurnal Ventilator Vol. 2 No. 3 (2024): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v2i3.1372

Abstract

Crohn's disease is a chronic inflammatory condition of the gastrointestinal tract that is often accompanied by psychological disorders such as depression. This study aims to analyze the impact of depression on the effectiveness of Crohn's disease treatment through a systematic review and meta-analysis. A literature search was conducted across electronic databases, including PubMed, Scopus, and Web of Science, for studies published in the last five years. Of the 1,247 articles identified, 28 studies met the inclusion criteria. The meta-analysis results indicate that Crohn's disease patients with depression have a lower remission rate (OR = 0.65, 95% CI: 0.54-0.78) and a higher relapse rate (HR = 1.58, 95% CI: 1.32-1.89) compared to patients without depression. Additionally, subgroup analysis reveals that the negative effects of depression are more pronounced in patients receiving biological therapy. These findings underscore the importance of a holistic approach in the management of Crohn's disease, considering the psychological aspects of patients to optimize treatment outcomes.
Kepuasan Hidup dan Pengaruhnya Terhadap Keberhasilan Pengobatan Penyakit Lupus Ika Sandra Dewi; M. Agung Rahmadi; Helsa Nasution; Luthfiah Mawar; Milna Sari
Jurnal Ventilator Vol. 2 No. 3 (2024): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v2i3.1379

Abstract

This study examines the relationship between life satisfaction and the effectiveness of systemic lupus erythematosus (SLE) treatment through a systematic review and meta-analysis of 32 studies (N=8,746) published between 2018 and 2023. The analysis reveals a moderate negative correlation between life satisfaction and lupus disease activity (r=-0.38, 95% CI: -0.44 to -0.32, p<0.001). More specifically, the data demonstrate a strong positive correlation between life satisfaction and quality of life in the context of health (r=0.52, 95% CI: 0.47-0.57, p<0.001) and a moderate positive correlation with medication adherence (r=0.34, 95% CI: 0.28-0.40, p<0.001). Longitudinal analysis (n=6 studies) shows that early improvements in life satisfaction are significantly predictive of reductions in lupus disease activity (?=-0.24, p<0.001) and enhancements in quality of life (?=0.29, p<0.001) over six months to 2 years. Meta-regression analysis further identifies age (?=0.008, p=0.03) and disease duration (?=0.015, p=0.01) as significant moderators of the effect of life satisfaction on SLE treatment outcomes. These findings extend previous research by Diener and Chan (2011) on well-being and health and by Mok et al. (2019) on depression in SLE by emphasizing the specific role of life satisfaction in SLE management. The novelty of this study lies in its focus on life satisfaction rather than solely negative risk factors, highlighting the potential for life satisfaction-based interventions in the management of SLE. This research supports the integration of life satisfaction assessments and psychosocial interventions into standard SLE care protocols, offering new insights into the psychoimmunological approach to SLE treatment.
Pengaruh Emosi Positif Terhadap Hasil Pengobatan Penyakit Rheumatoid Arthritis Luthfiah Mawar; M. Agung Rahmadi; Helsa Nasution; Ika Sandra Dewi; Milna Sari
Jurnal Ventilator Vol. 2 No. 3 (2024): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v2i3.1389

Abstract

This study evaluates the impact of positive emotions on rheumatoid arthritis (RA) treatment outcomes through a meta-analysis of 47 studies (2015-2024) involving 12,384 patients. The primary findings reveal a significant positive correlation between positive emotions and improved RA treatment outcomes (r = 0.42, p < 0.001), with the strongest effects observed in enhanced quality of life (r = 0.51) and physical function (r = 0.45). Patients exhibiting high positive emotions demonstrated greater reductions in pain (d = 0.38), decreased inflammation (d = 0.29), and improved physical function (d = 0.45) compared to control groups. Moreover, moderator analyses uncovered stronger effects among elderly patients (? = 0.012, p = 0.025) and those with longer RA duration (? = 0.018, p = 0.009). Finally, mediational analyses indicated that positive emotions contributed to improved treatment adherence (indirect effect = 0.09, 95% CI [0.05, 0.13]) and increased physical activity (indirect effect = 0.07, 95% CI [0.03, 0.11]) in RA patients. These findings extend Fredrickson's (2001) Broaden-and-Build theory and support Keefe et al.'s (2002) biopsychosocial model. Compared to meta-analyses by Brosseau et al. (2018) and Zhou et al. (2020), this study provides more comprehensive evidence on the role of positive emotions in various RA treatment outcomes. The novelty of this research lies in the analysis of previously unexplored mediating and moderating mechanisms, as well as a comparison of effectiveness with pharmacological interventions (SMD = 0.18, 95% CI [-0.05, 0.41], p = 0.124). These results support the integration of positive emotion-based interventions in RA management and expand upon Strand et al.'s (2019) findings on patient expectations in RA treatment.
Co-Authors Ika Sandra Dewi Luthfiah Mawa Luthfiah Mawar M. Agung Rahmadi Milna Sari Romaito Nasution